Risk Factors for Sepsis Based on Sepsis-3 Criteria after Orthotopic Liver Transplantation
Joint Authors
Wang, Yan-ling
Yuan, Dongdong
Huang, Fei
Gu, Yu
Liu, Dezhao
Zhang, Zheng
Zhou, Niman
Liang, Jiani
Lu, Changyin
Hei, Ziqing
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Sepsis is a common complication of solid organ transplant procedures and, in particular, can affect the prognosis of orthotopic liver transplantation (OLT).
This retrospective study determined the pre-, peri-, and postoperative risk factors for sepsis after OLT, using as reference the 2016 Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).
Pre-, peri-, and postoperative clinical data of the sepsis-positive (n=85) and sepsis-negative (n=41) groups were analyzed for potential risk factors of OLT-related sepsis.
The sepsis-positive patients had a significantly higher rate of dialysis (49.4%), longer time under mechanical ventilation (1.5 d), higher hospitalization costs (0.41 million RMB), and worse survival rate (68.5%), compared with the sepsis-negative patients (4.8%, 1 d, 0.30 million RMB, and 73.1%, resp.).
The multivariate logistic analysis identified the following as risk factors for OLT-related sepsis: preoperative Child-Pugh grade C (OR 10.43; 95% CI 2.081–52.292; P=0.004), preoperative hypercalcemia (OR 6.372; 95% CI 1.693–23.98; P=0.006), and perioperative acidosis (OR 6.364; 95% CI 1.196–33.869; P=0.030).
Patients with preoperative Child-Pugh grade C, preoperative hypercalcemia, or perioperative acidosis are at higher risk for developing sepsis after OLT.
When any of these problems occur, timely sepsis management should be planned.
American Psychological Association (APA)
Wang, Yan-ling& Gu, Yu& Huang, Fei& Liu, Dezhao& Zhang, Zheng& Zhou, Niman…[et al.]. 2018. Risk Factors for Sepsis Based on Sepsis-3 Criteria after Orthotopic Liver Transplantation. Mediators of Inflammation،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1204356
Modern Language Association (MLA)
Wang, Yan-ling…[et al.]. Risk Factors for Sepsis Based on Sepsis-3 Criteria after Orthotopic Liver Transplantation. Mediators of Inflammation No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1204356
American Medical Association (AMA)
Wang, Yan-ling& Gu, Yu& Huang, Fei& Liu, Dezhao& Zhang, Zheng& Zhou, Niman…[et al.]. Risk Factors for Sepsis Based on Sepsis-3 Criteria after Orthotopic Liver Transplantation. Mediators of Inflammation. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1204356
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204356