Role of Histamine in Modulating the Immune Response and Inflammation
Joint Authors
Sato, Maria Notomi
Branco, Anna Cláudia Calvielli Castelo
Yoshikawa, Fábio Seiti Yamada
Pietrobon, Anna Julia
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-27
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, and leukotrienes, impact the immune system, usually as proinflammatory factors.
Other mediators act as regulatory components to establish homeostasis after injury or prevent the inflammatory process.
Histamine, a biogenic vasoactive amine, causes symptoms such as allergies and has a pleiotropic effect that is dependent on its interaction with its four histamine receptors.
In this review, we discuss the dualistic effects of histamine: how histamine affects inflammation of the immune system through the activation of intracellular pathways that induce the production of inflammatory mediators and cytokines in different immune cells and how histamine exerts regulatory functions in innate and adaptive immune responses.
We also evaluate the interactions between these effects.
American Psychological Association (APA)
Branco, Anna Cláudia Calvielli Castelo& Yoshikawa, Fábio Seiti Yamada& Pietrobon, Anna Julia& Sato, Maria Notomi. 2018. Role of Histamine in Modulating the Immune Response and Inflammation. Mediators of Inflammation،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1204485
Modern Language Association (MLA)
Branco, Anna Cláudia Calvielli Castelo…[et al.]. Role of Histamine in Modulating the Immune Response and Inflammation. Mediators of Inflammation No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1204485
American Medical Association (AMA)
Branco, Anna Cláudia Calvielli Castelo& Yoshikawa, Fábio Seiti Yamada& Pietrobon, Anna Julia& Sato, Maria Notomi. Role of Histamine in Modulating the Immune Response and Inflammation. Mediators of Inflammation. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1204485
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204485