Anti-Inflammatory and Immunomodulatory Effects of Barberry (Berberis vulgaris) and Its Main Compounds
Joint Authors
Peluso, Ilaria
Mardaneh, Jalal
Aiello, Paola
Jouybari, Leila
Ghorat, Fereshteh
Kooti, Wesam
Kalmarzi, Rasool Nasiri
Naleini, Seyyed Nima
Ashtary-Larky, Damoon
Rafi, Alireza
Heidari, Nishteman
Sharifian, Faezeh
Helbi, Sobhan
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Berberis vulgaris is a well-known herb in Iran that is widely used as a medicinal plant and a food additive.
The aim of this study was to investigate the anti-inflammatory and immunomodulatory effects of Barberry and its main compounds.
This narrative review was conducted by searching keywords such as B.
vulgaris, Barberry, immunomodulatory, anti-inflammatory, medicinal herbs, plants, and extract, separately or combined in various databases, such as Web of Sciences, PubMed, and Scopus.
According to the inclusion and exclusion criteria, just English language articles, which reported effective whole plants or herbal compounds, were included.
21 articles were reviewed in this study.
In the in vivo models (mice, rats, and human cells) and in the in vitro models (some organ cells such as the spleen, kidney, blood, and brain), B.
vulgaris and its main components showed anti-inflammatory effects in both models.
The main mechanisms were the shift of cell immune response to Th2, T reg induction, inhibition of inflammatory cytokines (IL-1, TNF, and IFN-γ), and stimulation of IL-4 and IL-10.
The induction of apoptosis in APCs and other effector cells was another important mechanism.
American Psychological Association (APA)
Kalmarzi, Rasool Nasiri& Naleini, Seyyed Nima& Ashtary-Larky, Damoon& Peluso, Ilaria& Jouybari, Leila& Rafi, Alireza…[et al.]. 2019. Anti-Inflammatory and Immunomodulatory Effects of Barberry (Berberis vulgaris) and Its Main Compounds. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1204493
Modern Language Association (MLA)
Kalmarzi, Rasool Nasiri…[et al.]. Anti-Inflammatory and Immunomodulatory Effects of Barberry (Berberis vulgaris) and Its Main Compounds. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1204493
American Medical Association (AMA)
Kalmarzi, Rasool Nasiri& Naleini, Seyyed Nima& Ashtary-Larky, Damoon& Peluso, Ilaria& Jouybari, Leila& Rafi, Alireza…[et al.]. Anti-Inflammatory and Immunomodulatory Effects of Barberry (Berberis vulgaris) and Its Main Compounds. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1204493
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204493