What and How Can Physical Activity Prevention Function on Parkinson’s Disease?
Joint Authors
Ji, Xinying
Wei, Jianshe
Fan, Baozhu
Jabeen, Riffat
Bo, Bing
Guo, Chunlei
Han, Mengjie
Zhang, Hui
Cen, Juan
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-14
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Aim.
This study was aimed at investigating the effects and molecular mechanisms of physical activity intervention on Parkinson’s disease (PD) and providing theoretical guidance for the prevention and treatment of PD.
Methods.
Four electronic databases up to December 2019 were searched (PubMed, Springer, Elsevier, and Wiley database), 176 articles were selected.
Literature data were analyzed by the logic analysis method.
Results.
(1) Risk factors of PD include dairy products, pesticides, traumatic brain injury, and obesity.
Protective factors include alcohol, tobacco, coffee, black tea, and physical activity.
(2) Physical activity can reduce the risk and improve symptoms of PD and the beneficial forms of physical activity, including running, dancing, traditional Chinese martial arts, yoga, and weight training.
(3) Different forms of physical activity alleviate the symptoms of PD through different mechanisms, including reducing the accumulation of α-syn protein, inflammation, and oxidative stress, while enhancing BDNF activity, nerve regeneration, and mitochondrial function.
Conclusion.
Physical activity has a positive impact on the prevention and treatment of PD.
Illustrating the molecular mechanism of physical activity-induced protective effect on PD is an urgent need for improving the efficacy of PD therapy regimens in the future.
American Psychological Association (APA)
Fan, Baozhu& Jabeen, Riffat& Bo, Bing& Guo, Chunlei& Han, Mengjie& Zhang, Hui…[et al.]. 2020. What and How Can Physical Activity Prevention Function on Parkinson’s Disease?. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1204504
Modern Language Association (MLA)
Fan, Baozhu…[et al.]. What and How Can Physical Activity Prevention Function on Parkinson’s Disease?. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1204504
American Medical Association (AMA)
Fan, Baozhu& Jabeen, Riffat& Bo, Bing& Guo, Chunlei& Han, Mengjie& Zhang, Hui…[et al.]. What and How Can Physical Activity Prevention Function on Parkinson’s Disease?. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1204504
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204504