General, 21-Day Postoperative Rehabilitation Program Has Beneficial Effect on Oxidative Stress Markers in Patients after Total Hip or Knee Replacement
Joint Authors
Skrzep-Poloczek, Bronisława
Chełmecka, Elżbieta
Poloczek, Jakub
Kazura, Wojciech
Dulska, Agnieszka
Idzik, Maciej
Jochem, Jerzy
Stygar, Dominika
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-25
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Imbalance in prooxidant-antioxidant equilibrium plays an important role in the progression of osteoarthritis (OA).
Postoperative rehabilitation significantly improves the functional activity of patients with OA.
We aimed to assess the effect of the general 21-day postoperative rehabilitation on the oxidative stress markers in patients after total hip arthroplasty or knee replacement.
Patients (n =41) started individually designed postoperative rehabilitation ca.
90 days after endoprosthesis implantation.
We used the six-minute walk test (6MWT) to quantify the changes in their exercise capacity.
We analyzed the oxidative stress markers: total antioxidant capacity (TAC), total superoxide dismutase (SOD), Cu-Zn-superoxide dismutase (CuZnSOD) and ceruloplasmin (Cp) activity, malondialdehyde (MDA) and lipofuscin (LPS) concentration in patients serum to asses changes in the oxidative stress intensity.
We found that after 21-days postoperative rehabilitation program: the average distance walked by patients increased by 69 m; TAC increased by 0.20 ± 0.14 mmol/l; both SOD isoforms activities increased by 1.6 (±1.7) and 1.72 (±1.5) NU/ml, respectively; but Cp activity decreased by 1.8 (0.7-3.7) mg/dl.
Also, we observed lower concentrations of lipid peroxidation markers: by 19.6 ± 24.4 μmol/l for MDA and by 0.4 ± 0.5 RF for LPS.
A 21-day postoperative rehabilitation program effectively reduces oxidative processes, which helps the patients after total hip or knee replacement in a successful recovery.
American Psychological Association (APA)
Skrzep-Poloczek, Bronisława& Poloczek, Jakub& Chełmecka, Elżbieta& Kazura, Wojciech& Dulska, Agnieszka& Idzik, Maciej…[et al.]. 2020. General, 21-Day Postoperative Rehabilitation Program Has Beneficial Effect on Oxidative Stress Markers in Patients after Total Hip or Knee Replacement. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1204564
Modern Language Association (MLA)
Skrzep-Poloczek, Bronisława…[et al.]. General, 21-Day Postoperative Rehabilitation Program Has Beneficial Effect on Oxidative Stress Markers in Patients after Total Hip or Knee Replacement. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1204564
American Medical Association (AMA)
Skrzep-Poloczek, Bronisława& Poloczek, Jakub& Chełmecka, Elżbieta& Kazura, Wojciech& Dulska, Agnieszka& Idzik, Maciej…[et al.]. General, 21-Day Postoperative Rehabilitation Program Has Beneficial Effect on Oxidative Stress Markers in Patients after Total Hip or Knee Replacement. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1204564
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204564