Utilization of amniotic membrane graft for repair of the tympanic membrane perforation

Abstract EN

Myringoplasty is necessary to control infection, protect the middle ear and restore hearing.

Amniotic membrane, which used widely in grafting of the conjunctiva, supposed to be the new tympanic membrane graft .This study carried out to evaluate the utilization of amniotic membrane graft versus temporalis fascia graft in myringoplasty.

Materials & Methods: Sixty-four patients with the diagnosis of chronic suppurative otitis media without cholesteatoma undergo myringoplasty divided randomly into 2 groups: - the control group (temporalis fascia group, TFG) and the study group (the amniotic membrane group , AMG ).

All patients subjected to detailed medical history, complete ENT examinations and audiological test including pure tone audiometry (pre & postoperative).

Results: The mean operation duration for the temporalis fascia group was 75.3±9.4 minutes, while was 54.3±8.3 minutes for the amniotic membrane group which shows a statistically significant lower than temporalis fascia group (p<0.01).

The overall healing success rate in the TFG group was 87.5%, while 84.4% in AMG group without any significant difference between both groups.

Conclusion: Utilization of amniotic membrane graft in myringoplasty shows similar outcome to temporalis fascia graft