Combined Exercise Training Performed by Elderly Women Reduces Redox Indexes and Proinflammatory Cytokines Related to Atherogenesis

Joint Authors

Ramos, Luiz R.
Paes de Barros, Marcelo
Vieira, Rodolfo P.
Bachi, Andre Luis Lacerda
Amirato, Gislene R.
Vaisberg, Mauro
de Andrade, Paula B. M.
Victorino, Angélica B.
Gravina, Claudia F.
Lopes, José D.
Maranhão, Raul Cavalcante

Source

Oxidative Medicine and Cellular Longevity

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-08-05

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Biology

Abstract EN

Cardiovascular benefits for the general population of combined aerobic-resistance exercise training are well-known, but the impact of this exercise training modality on the plasma lipid, inflammatory, and antioxidant status in elderly women that are exposed to a great risk of developing ischemic cardio- and cerebrovascular diseases has not been well investigated.

So, we aimed to evaluate the plasma lipids, oxidative stress, and inflammatory cytokines in 27 elderly women (TRAINED group, 69.1±8.1 yrs) that were performing moderate intensity combined aerobic-resistance exercise training (3 times/week for at least 18 months) and in 27 sedentary elderly women (SED group, 72.0±6.4 yrs), not submitted to exercise training for at least 5 yrs.

Our results showed that BMI was lower in the TRAINED group than in the SED group (25.1±3.2 vs.

28.7±5.1, p<0.05).

The TRAINED group had lower glycemia (92±3 vs.

118±12, p<0.05), glycated hemoglobin (5.9±0.1 vs.

6.4±0.2, p<0.05), and triglycerides (98 (75-122) vs.

139 (109-214), p<0.01); equal total cholesterol (199 (175-230) vs.

194 (165-220)), LDL-cholesterol (108 (83-133) vs.

109 (98-136)), and non-HDL-cholesterol (54 (30-74) vs.

62 (26-80)); and also higher HDL-cholesterol (64 (52-77) vs.

52 (44-63), p<0.01) and LDL-C/oxLDL ratio (13378±2570 vs.

11639±3113, p<0.05) compared to the SED group.

Proinflammatory cytokines as IL-1β (11.31±2.4 vs.

28.01±4.7, p<0.05), IL-6 (26.25±7.4 vs.

49.41±17.8, p<0.05), and TNF-α (25.72±2.8 vs.

51.73±4.2, p<0.05) were lower in the TRAINED group than in the SED group.

The TRAINED group had lower total peroxides (26.3±7.4 vs.

49.0±17.8, p<0.05) and oxidized LDL (1551±50.33 vs.

1773±74, p<0.02) and higher total antioxidant capacity (26.25±7.4 vs.

49.41±17.8, p<0.001) compared to the SED group.

In conclusion, in TRAINED women, BMI was lower, plasma lipid profile was better, plasma oxidative stress was diminished, and there was less expression of proinflammatory interleukins than in SED, suggesting that combined aerobic-resistance exercise training may promote the protection against the complications of ischemic cardio- and cerebrovascular disease in elderly women.

American Psychological Association (APA)

Bachi, Andre Luis Lacerda& Paes de Barros, Marcelo& Vieira, Rodolfo P.& Amirato, Gislene R.& de Andrade, Paula B. M.& Victorino, Angélica B.…[et al.]. 2019. Combined Exercise Training Performed by Elderly Women Reduces Redox Indexes and Proinflammatory Cytokines Related to Atherogenesis. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1204631

Modern Language Association (MLA)

Bachi, Andre Luis Lacerda…[et al.]. Combined Exercise Training Performed by Elderly Women Reduces Redox Indexes and Proinflammatory Cytokines Related to Atherogenesis. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1204631

American Medical Association (AMA)

Bachi, Andre Luis Lacerda& Paes de Barros, Marcelo& Vieira, Rodolfo P.& Amirato, Gislene R.& de Andrade, Paula B. M.& Victorino, Angélica B.…[et al.]. Combined Exercise Training Performed by Elderly Women Reduces Redox Indexes and Proinflammatory Cytokines Related to Atherogenesis. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1204631

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1204631