Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy

Joint Authors

Yan, Liang-Jun
Tao, Ran
Ma, Wei-Xing
Li, Chun-Yan
Wang, Xin-Ping

Source

Oxidative Medicine and Cellular Longevity

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-05-30

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Biology

Abstract EN

The goal of this review was to summarize reported studies focusing on cellular reductive stress-induced mitochondrial dysfunction, cardiomyopathy, dithiothreitol- (DTT-) induced reductive stress, and reductive stress-related free radical reactions published in the past five years.

Reductive stress is considered to be a double-edged sword in terms of antioxidation and disease induction.

As many underlying mechanisms are still unclear, further investigations are obviously warranted.

Nonetheless, reductive stress is thought to be caused by elevated levels of cellular reducing power such as NADH, glutathione, and NADPH; and this area of research has attracted increasing attention lately.

Albeit, we think there is a need to conduct further studies in identifying more indicators of the risk assessment and prevention of developing heart damage as well as exploring more targets for cardiomyopathy treatment.

Hence, it is expected that further investigation of underlying mechanisms of reductive stress-induced mitochondrial dysfunction will provide novel insights into therapeutic approaches for ameliorating reductive stress-induced cardiomyopathy.

American Psychological Association (APA)

Ma, Wei-Xing& Li, Chun-Yan& Tao, Ran& Wang, Xin-Ping& Yan, Liang-Jun. 2020. Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1204736

Modern Language Association (MLA)

Ma, Wei-Xing…[et al.]. Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1204736

American Medical Association (AMA)

Ma, Wei-Xing& Li, Chun-Yan& Tao, Ran& Wang, Xin-Ping& Yan, Liang-Jun. Reductive Stress-Induced Mitochondrial Dysfunction and Cardiomyopathy. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1204736

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1204736