Correlation of Redox Status with Procalcitonin and C-reactive Protein in Septic Patients
Joint Authors
Milinkovic, Ivan
Bolevich, Sergey
Turnic, Tamara Nikolic
Petrovic, Jasna
Zivkovic, Vladimir
Andjic, Marijana
Draginic, Nevena
Stojanovic, Aleksandra
Jakovljevic, Vladimir
Jevdjic, Jasna
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-04
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Based on the role of oxidative stress in the pathophysiological mechanisms of sepsis and the importance of PCT as a clinically applicable biomarker for early detection of inflammatory response initiation, we aimed this study at examining the correlation between PCT levels and oxidative stress parameters (prooxidants and antioxidants) in patients with sepsis.
This study was designed as a case-series prospective clinical study which involved 103 critically ill patients and 17 healthy participants with diagnosis of sepsis/septic shock (over 18 years of age, both gender) admitted to the Intensive Care Unit (ICU) of Valjevo General Hospital in Serbia.
All subjects were divided into patients who were operated on/underwent surgery before sampling and have sepsis (n=24), patients who were operated on/underwent surgery before sampling and have septic shock (n=25), patients who were not operated on/did not undergo surgery before sampling and have sepsis (n=26), patients who were not operated on/did not undergo surgery before sampling and have septic shock (n=28), and participants who are healthy (n=17).
PCT has confirmed a positive correlation with prooxidants and type of critical illness, and performing surgical intervention diminished oxidative stress in patients with septic shock.
Prognosis in critically ill patients was strongly associated with PCT levels but not with nonspecifically C-reactive protein.
American Psychological Association (APA)
Petrovic, Jasna& Turnic, Tamara Nikolic& Zivkovic, Vladimir& Andjic, Marijana& Draginic, Nevena& Stojanovic, Aleksandra…[et al.]. 2020. Correlation of Redox Status with Procalcitonin and C-reactive Protein in Septic Patients. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1204749
Modern Language Association (MLA)
Petrovic, Jasna…[et al.]. Correlation of Redox Status with Procalcitonin and C-reactive Protein in Septic Patients. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1204749
American Medical Association (AMA)
Petrovic, Jasna& Turnic, Tamara Nikolic& Zivkovic, Vladimir& Andjic, Marijana& Draginic, Nevena& Stojanovic, Aleksandra…[et al.]. Correlation of Redox Status with Procalcitonin and C-reactive Protein in Septic Patients. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1204749
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204749