Implication of Gut Microbiota in Cardiovascular Diseases
Joint Authors
Zhu, Ping
Nasser, M. I.
Zhao, Mingyi
Zhang, Xueyan
Zhou, Wenyi
Cheng, Yiyu
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-26
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Emerging evidence has identified the association between gut microbiota and various diseases, including cardiovascular diseases (CVDs).
Altered intestinal flora composition has been described in detail in CVDs, such as hypertension, atherosclerosis, myocardial infarction, heart failure, and arrhythmia.
In contrast, the importance of fermentation metabolites, such as trimethylamine N-oxide (TMAO), short-chain fatty acids (SCFAs), and secondary bile acid (BA), has also been implicated in CVD development, prevention, treatment, and prognosis.
The potential mechanisms are conventionally thought to involve immune regulation, host energy metabolism, and oxidative stress.
However, numerous types of programmed cell death, including apoptosis, autophagy, pyroptosis, ferroptosis, and clockophagy, also serve as a key link in microbiome-host cross talk.
In this review, we introduced and summarized the results from recent studies dealing with the relationship between gut microbiota and cardiac disorders, highlighting the role of programmed cell death.
We hope to shed light on microbiota-targeted therapeutic strategies in CVD management.
American Psychological Association (APA)
Zhou, Wenyi& Cheng, Yiyu& Zhu, Ping& Nasser, M. I.& Zhang, Xueyan& Zhao, Mingyi. 2020. Implication of Gut Microbiota in Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1204840
Modern Language Association (MLA)
Zhou, Wenyi…[et al.]. Implication of Gut Microbiota in Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1204840
American Medical Association (AMA)
Zhou, Wenyi& Cheng, Yiyu& Zhu, Ping& Nasser, M. I.& Zhang, Xueyan& Zhao, Mingyi. Implication of Gut Microbiota in Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1204840
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204840