Cardiovascular Risk Factors and Haematological Indexes of Inflammation in Paralympic Athletes with Different Motor Impairments
Joint Authors
Peluso, Ilaria
Palmery, Maura
Romano, Silvio
Aiello, Paola
Bernardi, Marco
Fedullo, Anna Lucia
Di Giacinto, Barbara
Squeo, Maria Rosaria
Dante, Donatella
Magaudda, Ludovico
Spataro, Antonio
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-18
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Haematological indexes of both inflammation and platelet activation have been suggested as predictive markers of cardiovascular disease (CVD), which has high prevalence in Paralympic athletes (PA).
Different mechanisms could play a role in increasing CVD risk in PA with spinal cord injury (PA-SCI), lower limb amputation (PA-LLA), or upper limb impairment (PA-ULI).
We compared, in 4 groups of PA competing in power, intermittent (mixed metabolism), and endurance sports, Framingham Risk Score (FRS), metabolic syndrome criteria (MetS-C), inflammation (INFLA) Score, 5 haematological indexes of platelet activation (mean platelet volume (MPV), platelet distribution width (PDW), and the ratios between MPV and platelet (MPVPR), between MPV and lymphocyte (MPVLR), and between PDW and lymphocyte (PDWLR)) and the endogenous antioxidants uric acid (UA) and bilirubin (BR).
A retrospective chart review of PA from preparticipation examinations’ records (London 2012 and Sochi 2014 Paralympics) was performed.
We included 25 PA-SCI (13 with high and 12 with low lesion, PA-SCI-H and PA-SCI-L), 15 PA-LLA, and 10 PA-ULI.
FRS and INFLA Score did not differ among groups, but PA-SCI-H had lower HDL, compared to PA-SCI-L and PA-ULI.
PA-LLA had more MetS diagnostic criteria with significant higher glucose levels than other groups.
PA-SCI-H had significantly lower lymphocytes’ count compared to PA-LLA and higher MPV, PDW, MPVPR, MPVLR, and PDWLR.
SCI-H had lower BR, haemoglobin, haematocrit, proteins, and creatinine.
No interaction was found between the 3 kinds of sitting sports and the 2 groups of health conditions (PA-SCI and PA-LLA).
In conclusion, PA-LLA had a higher cardiometabolic risk, whereas PA-SCI-H had a higher platelet-derived cardiovascular risk.
Further larger studies are needed to investigate the relationship between indexes of inflammation/oxidation and dietary habit, body composition, and physical fitness/performance in PA with motor impairments.
American Psychological Association (APA)
Bernardi, Marco& Fedullo, Anna Lucia& Di Giacinto, Barbara& Squeo, Maria Rosaria& Aiello, Paola& Dante, Donatella…[et al.]. 2019. Cardiovascular Risk Factors and Haematological Indexes of Inflammation in Paralympic Athletes with Different Motor Impairments. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1204859
Modern Language Association (MLA)
Bernardi, Marco…[et al.]. Cardiovascular Risk Factors and Haematological Indexes of Inflammation in Paralympic Athletes with Different Motor Impairments. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1204859
American Medical Association (AMA)
Bernardi, Marco& Fedullo, Anna Lucia& Di Giacinto, Barbara& Squeo, Maria Rosaria& Aiello, Paola& Dante, Donatella…[et al.]. Cardiovascular Risk Factors and Haematological Indexes of Inflammation in Paralympic Athletes with Different Motor Impairments. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1204859
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204859