Dietary Total Antioxidant Capacity and Gestational Diabetes Mellitus: A Case-Control Study
Joint Authors
Daneshzad, Elnaz
Tehrani, Hatav
Bellissimo, Nick
Azadbakht, Leila
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Elevated oxidative stress status has been reported among pregnant women with gestational diabetes mellitus (GDM).
In diabetic condition, glucose and lipid peroxidation, and alteration in antioxidant defense lead to increased free radicals.
The objective of this study was to investigate the association between dietary total antioxidant capacity (DTAC) and GDM.
Methods.
This hospital-based case-control study was conducted in 463 pregnant women (healthy, n=263; GDM, n=200).
Anthropometric indices, blood pressure, and biochemical analyses were measured.
Dietary intake was assessed by the average of three 24-hour dietary intake records.
DTAC was calculated by three indices: ferric reducing ability of plasma (FRAP), total radical-trapping antioxidant parameter (TRAP), and Trolox equivalent antioxidant capacity (TEAC).
Multivariable logistic regression was performed to examine the relationship between DTAC and GDM risk in crude and adjusted models.
Results.
The mean age and BMI were 28.33±6.23 years and 29.67±4.73 kg/m2, respectively.
Total energy, protein, and selenium intakes were significantly higher in cases than controls (P<0.05).
Moreover, intakes of carbohydrate, vitamins C, B6, and A, manganese, fruits, fruit juices, vegetables, legumes, and FRAP were significantly lower in cases than controls (P<0.05).
The risk of gestational diabetes mellitus was 85% lower among those in the highest tertile of FRAP (OR: 0.15; 95% CI: 0.08-0.29).
There was no significant association between the risk of GDM and TRAP (OR: 1.62; 95% CI: 0.94-2.79) as well as TEAC (OR: 1.56; 95% CI: 0.89-2.72).
Conclusion.
Pregnant women who were in the highest tertile of FRAP were at lower risk of GDM.
However, larger prospective studies are needed to confirm our findings.
American Psychological Association (APA)
Daneshzad, Elnaz& Tehrani, Hatav& Bellissimo, Nick& Azadbakht, Leila. 2020. Dietary Total Antioxidant Capacity and Gestational Diabetes Mellitus: A Case-Control Study. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1204874
Modern Language Association (MLA)
Daneshzad, Elnaz…[et al.]. Dietary Total Antioxidant Capacity and Gestational Diabetes Mellitus: A Case-Control Study. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1204874
American Medical Association (AMA)
Daneshzad, Elnaz& Tehrani, Hatav& Bellissimo, Nick& Azadbakht, Leila. Dietary Total Antioxidant Capacity and Gestational Diabetes Mellitus: A Case-Control Study. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1204874
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204874