Mitochondria-Derived Damage-Associated Molecular Patterns in Sepsis: From Bench to Bedside
Joint Authors
Wu, Xiuwen
Ren, Jianan
Li, Sicheng
Hu, Qiongyuan
Huang, Jinjian
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-05-08
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Sepsis is one of the most serious health hazards.
Current research suggests that the pathogenesis of sepsis is mediated by both pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Mitochondria are among the most important organelles in cells and determine their life and death.
A variety of mitochondria-derived DAMPs (mtDAMPs) are similar to bacteria because mitochondria are derived from bacteria according to the mitochondrial endosymbiotic theory.
Their activated signaling pathways extensively affect organ functions, the immune system, and metabolic functions in sepsis.
In this review, we describe the essential roles of mtDAMPs in sepsis and discuss their research prospects and clinical importance.
American Psychological Association (APA)
Li, Sicheng& Hu, Qiongyuan& Huang, Jinjian& Wu, Xiuwen& Ren, Jianan. 2019. Mitochondria-Derived Damage-Associated Molecular Patterns in Sepsis: From Bench to Bedside. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1204900
Modern Language Association (MLA)
Li, Sicheng…[et al.]. Mitochondria-Derived Damage-Associated Molecular Patterns in Sepsis: From Bench to Bedside. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1204900
American Medical Association (AMA)
Li, Sicheng& Hu, Qiongyuan& Huang, Jinjian& Wu, Xiuwen& Ren, Jianan. Mitochondria-Derived Damage-Associated Molecular Patterns in Sepsis: From Bench to Bedside. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1204900
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204900