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Recent Research on Methods to Improve Tumor Hypoxia Environment
Joint Authors
Zhu, Dan
Zhu, Xiao-Hua
Du, Jun-Xi
Ren, Shen-Zhen
Chen, Kun
Zhu, Hai-Liang
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-02
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
Cancer is a major disease burden worldwide.
In recent years, in addition to surgical resection, radiotherapy and chemotherapy are recognized as the most effective methods for treating solid tumors.
These methods have been introduced to treat tumors of different origins and stages clinically.
However, due to insufficient blood flow and oxygen (O2) supply in solid tumors, hypoxia is caused, leading to decreased sensitivity of tumor cells and poor therapeutic effects.
In addition, hypoxia will also lead to resistance to most anticancer drugs, accelerate malignant progress, and increase metastasis.
In solid tumors, adequate O2 supply and adequate delivery of anticancer drugs are essential to improve radiotherapy and chemotherapy sensitivity.
In recent decades, the researches on relieving tumor hypoxia have attracted researchers’ extensive attention and achieved good results.
However, as far as we know, there is no detailed review of the researches on alleviating tumor hypoxia.
Therefore, in this contribution, we hope to give an overview of the researches on methods to improve tumor hypoxia environment and summarize their effect and application in tumor therapy, to provide a methodological reference for the research and development of new antitumor agents.
American Psychological Association (APA)
Zhu, Xiao-Hua& Du, Jun-Xi& Zhu, Dan& Ren, Shen-Zhen& Chen, Kun& Zhu, Hai-Liang. 2020. Recent Research on Methods to Improve Tumor Hypoxia Environment. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1204927
Modern Language Association (MLA)
Zhu, Xiao-Hua…[et al.]. Recent Research on Methods to Improve Tumor Hypoxia Environment. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-18.
https://search.emarefa.net/detail/BIM-1204927
American Medical Association (AMA)
Zhu, Xiao-Hua& Du, Jun-Xi& Zhu, Dan& Ren, Shen-Zhen& Chen, Kun& Zhu, Hai-Liang. Recent Research on Methods to Improve Tumor Hypoxia Environment. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1204927
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1204927