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Skin-Related Properties and Constituents from the Aerial Parts Extract of Persicaria senticosa
Joint Authors
Choi, Yun-Hyeok
Lee, Jae Yeon
Lee, Ji Eun
Jung, Yeon Woo
Jeong, Wonsik
Hong, Seong Su
Cho, Young-Rak
Choi, Chun Whan
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-21
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
In the course of screening for cosmetic ingredients by measuring antioxidant and antiwrinkle and whitening and anti-inflammatory activities, skin-related activity was tested using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging, elastase inhibition, tyrosinase inhibition, and nitric oxide assay.
Several Polygonaseae extracts were found to show potent activity.
The results showed that the Persicaria senticosa methanolic extract has the 1,1diphenyl-2picrylhydrazyl (DPPH) and ABTS radical scavenging activities (IC50 61.0 and 17.5 μg/mL).
In the elastase inhibition assay and nitric oxide assay, the IC50 of methanolic extract of Persicaria senticosa was 739.7 μg/mL and 71.8 μg/mL.
The Persicaria senticosa 70% ethanolic extract partitioned with n-hexane, CH2Cl2, EtOAc, n-BuOH, and aqueous fractions.
The purification of EtOAc soluble layer was by column chromatography separation and MPLC analysis of Compounds 1-7.
It was identified as loliolide (1), quercetin-3-O-glucoside (2), quercetin-3-O-glucuronide (3), 4-methoxy caftraric acid (4), kaempferol-3-(6-methylglucuronide) (5), quercetin-3-(6-methylglucuronide) (6), and quercetin (7).
Structure was elucidated by a combination of 1D and 2D NMR and MS spectrometry as well as comparison with reported literatures.
Radical scavenging effect on DPPH, tyrosinase inhibition, and nitric oxide assay on several compounds from Persicaria senticosa was found to show potent activity.
The results showed that Compound 7 has the NO assay (IC5029.7 μM).
For DPPH, the IC50 of Compounds 2, 3, 5, and 7 was 39.6, 31.2, 37.0, and 22.7 μM.
In tyrosinase inhibitory activity, the IC50 of Compound 7 was 14.3 μM.
American Psychological Association (APA)
Choi, Yun-Hyeok& Lee, Jae Yeon& Lee, Ji Eun& Jung, Yeon Woo& Jeong, Wonsik& Hong, Seong Su…[et al.]. 2020. Skin-Related Properties and Constituents from the Aerial Parts Extract of Persicaria senticosa. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1205169
Modern Language Association (MLA)
Choi, Yun-Hyeok…[et al.]. Skin-Related Properties and Constituents from the Aerial Parts Extract of Persicaria senticosa. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1205169
American Medical Association (AMA)
Choi, Yun-Hyeok& Lee, Jae Yeon& Lee, Ji Eun& Jung, Yeon Woo& Jeong, Wonsik& Hong, Seong Su…[et al.]. Skin-Related Properties and Constituents from the Aerial Parts Extract of Persicaria senticosa. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1205169
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1205169