Galactose-Induced Skin Aging: The Role of Oxidative Stress
Joint Authors
Umbayev, Bauyrzhan
Askarova, Sholpan
Almabayeva, Aigul
Saliev, Timur
Masoud, Abdul-Razak
Bulanin, Denis
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-17
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Skin aging has been associated with a higher dietary intake of carbohydrates, particularly glucose and galactose.
In fact, the carbohydrates are capable of damaging the skin’s vital components through nonenzymatic glycation, the covalent attachment of sugar to a protein, and subsequent production of advanced glycation end products (AGEs).
This review is focused on the role of D-galactose in the development of skin aging and its relation to oxidative stress.
The interest in this problem was dictated by recent findings that used in vitro and in vivo models.
The review highlights the recent advances in the underlying molecular mechanisms of D-galactose-mediated cell senescence and cytotoxicity.
We have also proposed the possible impact of galactosemia on skin aging and its clinical relevance.
The understanding of molecular mechanisms of skin aging mediated by D-galactose can help dermatologists optimize methods for prevention and treatment of skin senescence and aging-related skin diseases.
American Psychological Association (APA)
Umbayev, Bauyrzhan& Askarova, Sholpan& Almabayeva, Aigul& Saliev, Timur& Masoud, Abdul-Razak& Bulanin, Denis. 2020. Galactose-Induced Skin Aging: The Role of Oxidative Stress. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1205297
Modern Language Association (MLA)
Umbayev, Bauyrzhan…[et al.]. Galactose-Induced Skin Aging: The Role of Oxidative Stress. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-15.
https://search.emarefa.net/detail/BIM-1205297
American Medical Association (AMA)
Umbayev, Bauyrzhan& Askarova, Sholpan& Almabayeva, Aigul& Saliev, Timur& Masoud, Abdul-Razak& Bulanin, Denis. Galactose-Induced Skin Aging: The Role of Oxidative Stress. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1205297
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1205297