Addition of Wollastonite Fibers to Calcium Phosphate Cement Increases Cell Viability and Stimulates Differentiation of Osteoblast-Like Cells
Joint Authors
Duek, Eliana Aparecida de Rezende
Domingues, Juliana
Haussen, Moema
Motisuke, Mariana
Bertran, Celso Aparecido
Camilli, José Angelo
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Calcium phosphate cement (CPC) that is based on α-tricalcium phosphate (α-TCP) is considered desirable for bone tissue engineering because of its relatively rapid degradation properties.
However, such cement is relatively weak, restricting its use to areas of low mechanical stress.
Wollastonite fibers (WF) have been used to improve the mechanical strength of biomaterials.
However, the biological properties of WF remain poorly understood.
Here, we tested the response of osteoblast-like cells to being cultured on CPC reinforced with 5% of WF (CPC-WF).
We found that both types of cement studied achieved an ion balance for calcium and phosphate after 3 days of immersion in culture medium and this allowed subsequent long-term cell culture.
CPC-WF increased cell viability and stimulated cell differentiation, compared to nonreinforced CPC.
We hypothesize that late silicon release by CPC-WF induces increased cell proliferation and differentiation.
Based on our findings, we propose that CPC-WF is a promising material for bone tissue engineering applications.
American Psychological Association (APA)
Domingues, Juliana& Motisuke, Mariana& Bertran, Celso Aparecido& Haussen, Moema& Duek, Eliana Aparecida de Rezende& Camilli, José Angelo. 2017. Addition of Wollastonite Fibers to Calcium Phosphate Cement Increases Cell Viability and Stimulates Differentiation of Osteoblast-Like Cells. The Scientific World Journal،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1205372
Modern Language Association (MLA)
Domingues, Juliana…[et al.]. Addition of Wollastonite Fibers to Calcium Phosphate Cement Increases Cell Viability and Stimulates Differentiation of Osteoblast-Like Cells. The Scientific World Journal No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1205372
American Medical Association (AMA)
Domingues, Juliana& Motisuke, Mariana& Bertran, Celso Aparecido& Haussen, Moema& Duek, Eliana Aparecida de Rezende& Camilli, José Angelo. Addition of Wollastonite Fibers to Calcium Phosphate Cement Increases Cell Viability and Stimulates Differentiation of Osteoblast-Like Cells. The Scientific World Journal. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1205372
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1205372