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Emerging Role of Ferroptosis in Acute Kidney Injury
Joint Authors
Yang, Shikun
Zhang, Wei
Hu, Zhaoxin
Wu, Xueqin
He, Dong
Cao, Ke
Zhang, Hao
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Acute kidney injury (AKI) is a heterogeneous group of critical disease conditions with high incidence and mortality.
Vasoconstriction, oxidative stress, apoptosis, and inflammation are generally thought to be the main pathogenic mechanisms of AKI.
Ferroptosis is a type of iron-dependent nonapoptotic cell death characterized by membrane lipid peroxide accumulation and polyunsaturated fatty acid consumption, and it plays essential roles in many diseases, including cancers and neurologic diseases.
Recent studies have revealed an emerging role of ferroptosis in the pathophysiological processes of AKI.
Here, in the present review, we summarized the most recent discoveries on the role of ferroptosis in the pathogenesis of AKI as well as its therapeutic potential in AKI.
American Psychological Association (APA)
Hu, Zhaoxin& Zhang, Hao& Yang, Shikun& Wu, Xueqin& He, Dong& Cao, Ke…[et al.]. 2019. Emerging Role of Ferroptosis in Acute Kidney Injury. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1205399
Modern Language Association (MLA)
Hu, Zhaoxin…[et al.]. Emerging Role of Ferroptosis in Acute Kidney Injury. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1205399
American Medical Association (AMA)
Hu, Zhaoxin& Zhang, Hao& Yang, Shikun& Wu, Xueqin& He, Dong& Cao, Ke…[et al.]. Emerging Role of Ferroptosis in Acute Kidney Injury. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1205399
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1205399