Chemistry and Biochemistry of Sulfur Natural Compounds: Key Intermediates of Metabolism and Redox Biology
Joint Authors
Mosca, Luciana
Fontana, Mario
Francioso, Antonio
Baseggio Conrado, Alessia
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-27, 27 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-30
Country of Publication
Egypt
No. of Pages
27
Main Subjects
Abstract EN
Sulfur contributes significantly to nature chemical diversity and thanks to its particular features allows fundamental biological reactions that no other element allows.
Sulfur natural compounds are utilized by all living beings and depending on the function are distributed in the different kingdoms.
It is no coincidence that marine organisms are one of the most important sources of sulfur natural products since most of the inorganic sulfur is metabolized in ocean environments where this element is abundant.
Terrestrial organisms such as plants and microorganisms are also able to incorporate sulfur in organic molecules to produce primary metabolites (e.g., methionine, cysteine) and more complex unique chemical structures with diverse biological roles.
Animals are not able to fix inorganic sulfur into biomolecules and are completely dependent on preformed organic sulfurous compounds to satisfy their sulfur needs.
However, some higher species such as humans are able to build new sulfur-containing chemical entities starting especially from plants’ organosulfur precursors.
Sulfur metabolism in humans is very complicated and plays a central role in redox biochemistry.
The chemical properties, the large number of oxidation states, and the versatile reactivity of the oxygen family chalcogens make sulfur ideal for redox biological reactions and electron transfer processes.
This review will explore sulfur metabolism related to redox biochemistry and will describe the various classes of sulfur-containing compounds spread all over the natural kingdoms.
We will describe the chemistry and the biochemistry of well-known metabolites and also of the unknown and poorly studied sulfur natural products which are still in search for a biological role.
American Psychological Association (APA)
Francioso, Antonio& Baseggio Conrado, Alessia& Mosca, Luciana& Fontana, Mario. 2020. Chemistry and Biochemistry of Sulfur Natural Compounds: Key Intermediates of Metabolism and Redox Biology. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-27.
https://search.emarefa.net/detail/BIM-1205568
Modern Language Association (MLA)
Francioso, Antonio…[et al.]. Chemistry and Biochemistry of Sulfur Natural Compounds: Key Intermediates of Metabolism and Redox Biology. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-27.
https://search.emarefa.net/detail/BIM-1205568
American Medical Association (AMA)
Francioso, Antonio& Baseggio Conrado, Alessia& Mosca, Luciana& Fontana, Mario. Chemistry and Biochemistry of Sulfur Natural Compounds: Key Intermediates of Metabolism and Redox Biology. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-27.
https://search.emarefa.net/detail/BIM-1205568
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1205568