![](/images/graphics-bg.png)
Hematopoietic Stem Cells and Mesenchymal Stromal Cells in Acute Radiation Syndrome
Joint Authors
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-13
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
With the extensive utilization of radioactive materials for medical, industrial, agricultural, military, and research purposes, medical researchers are trying to identify new methods to treat acute radiation syndrome (ARS).
Radiation may cause injury to different tissues and organs, but no single drug has been proven to be effective in all circumstances.
Radioprotective agents are always effective if given before irradiation, but many nuclear accidents are unpredictable.
Medical countermeasures that can be beneficial to different organ and tissue injuries caused by radiation are urgently needed.
Cellular therapy, especially stem cell therapy, has been a promising approach in ARS.
Hematopoietic stem cells (HSCs) and mesenchymal stromal cells (MSCs) are the two main kinds of stem cells which show good efficacy in ARS and have attracted great attention from researchers.
There are also some limitations that need to be investigated in future studies.
In recent years, there are also some novel methods of stem cells that could possibly be applied on ARS, like “drug” stem cell banks obtained from clinical grade human induced pluripotent stem cells (hiPSCs), MSC-derived products, and infusion of HSCs without preconditioning treatment, which make us confident in the future treatment of ARS.
This review focuses on major scientific and clinical advances of hematopoietic stem cells and mesenchymal stromal cells on ARS.
American Psychological Association (APA)
Qian, Liren& Cen, Jian. 2020. Hematopoietic Stem Cells and Mesenchymal Stromal Cells in Acute Radiation Syndrome. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1205575
Modern Language Association (MLA)
Qian, Liren& Cen, Jian. Hematopoietic Stem Cells and Mesenchymal Stromal Cells in Acute Radiation Syndrome. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1205575
American Medical Association (AMA)
Qian, Liren& Cen, Jian. Hematopoietic Stem Cells and Mesenchymal Stromal Cells in Acute Radiation Syndrome. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1205575
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1205575