Effect of Platelet-Rich Plasma on Intervertebral Disc Degeneration In Vivo and In Vitro: A Critical Review
Joint Authors
Chang, Yvang
Yang, Ming
Ke, Song
Zhang, Yu
Xu, Gang
Li, Zhonghai
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Intervertebral disc degeneration (IDD) is a globally occurring disease that represents a significant cause of socioeconomic problems.
Currently, the main method for treating IDD is surgery, including discectomy and vertebral fusion.
Several in vitro experiments demonstrated that platelet-rich plasma (PRP) could stimulate cell proliferation and extracellular matrix regeneration.
Additionally, in vivo experiments have proven that PRP injection could restore intervertebral disc height.
Clinical studies demonstrated that PRP injection could significantly relieve patient pain.
However, further studies are still required to clarify the roles of PRP in IDD prevention and treatment.
This review is aimed at summarizing and critically analyzing the current evidence regarding IDD treatment with PRP.
American Psychological Association (APA)
Chang, Yvang& Yang, Ming& Ke, Song& Zhang, Yu& Xu, Gang& Li, Zhonghai. 2020. Effect of Platelet-Rich Plasma on Intervertebral Disc Degeneration In Vivo and In Vitro: A Critical Review. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1205880
Modern Language Association (MLA)
Chang, Yvang…[et al.]. Effect of Platelet-Rich Plasma on Intervertebral Disc Degeneration In Vivo and In Vitro: A Critical Review. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1205880
American Medical Association (AMA)
Chang, Yvang& Yang, Ming& Ke, Song& Zhang, Yu& Xu, Gang& Li, Zhonghai. Effect of Platelet-Rich Plasma on Intervertebral Disc Degeneration In Vivo and In Vitro: A Critical Review. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1205880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1205880