Relationship between Oxidative Stress and Physical Activity in Women with Squamous Intraepithelial Lesions in a Cervical Cancer Control Program in the Brazilian Amazon
Joint Authors
Carneiro, Saul Rassy
da Silva Lima, Abner Ariel
de Fátima Silva Santos, Gleyce
de Oliveira, Cláudia Simone Baltazar
Almeida, Maria Cláudia Valente
da Conceição Nascimento Pinheiro, Maria
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Human papillomavirus (HPV) infection is recognized as the most common sexually transmitted disease in the world, and there is a consensus on its role in the etiology of preneoplastic epithelial changes in the cervix.
Through the process of lipid peroxidation, oxidative stress is found in the course of premalignant and malignant changes.
Moreover, the level of physical activity can exert an influence on markers of oxidative stress, lowering the serum levels of these markers.
Objective.
To determine the relationship between levels of malondialdehyde (MDA) and the level of physical activity in women with squamous intraepithelial lesion (SIL) of the cervix.
Methods.
A cross-sectional study was conducted with 46 women participating in a cervical cancer control program.
The women had been submitted to the cytopathological exam and were divided into two groups: 18 with SIL and 28 controls.
MDA concentrations were determined, and the International Physical Activity Questionnaire (IPAQ) was administered on the same day as the gynecological appointment (prior to the Papanicolaou test).
Results.
The SIL group had higher MDA levels than the control group (mean: 47.63±9.57 vs.
9.32±4.79, respectively) and a lower IPAQ score (median: 713.5 vs.
1875, respectively).
A weak correlation was found between the MDA level and IPAQ score (r2=−0.34, p=0.018).
Conclusion.
The women with SIL had higher levels of oxidative stress and were less physically active than the women in the control group.
These findings suggest that physical exercise exerts an influence on markers of oxidative stress in the development of intraepithelial squamous lesions.
American Psychological Association (APA)
Carneiro, Saul Rassy& da Silva Lima, Abner Ariel& de Fátima Silva Santos, Gleyce& de Oliveira, Cláudia Simone Baltazar& Almeida, Maria Cláudia Valente& da Conceição Nascimento Pinheiro, Maria. 2019. Relationship between Oxidative Stress and Physical Activity in Women with Squamous Intraepithelial Lesions in a Cervical Cancer Control Program in the Brazilian Amazon. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1205962
Modern Language Association (MLA)
Carneiro, Saul Rassy…[et al.]. Relationship between Oxidative Stress and Physical Activity in Women with Squamous Intraepithelial Lesions in a Cervical Cancer Control Program in the Brazilian Amazon. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1205962
American Medical Association (AMA)
Carneiro, Saul Rassy& da Silva Lima, Abner Ariel& de Fátima Silva Santos, Gleyce& de Oliveira, Cláudia Simone Baltazar& Almeida, Maria Cláudia Valente& da Conceição Nascimento Pinheiro, Maria. Relationship between Oxidative Stress and Physical Activity in Women with Squamous Intraepithelial Lesions in a Cervical Cancer Control Program in the Brazilian Amazon. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1205962
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1205962