Potential Protective and Therapeutic Roles of the Nrf2 Pathway in Ocular Diseases: An Update
Joint Authors
Zhang, Hong
Wang, Ming-xuan
Zhao, Jing
Li, Ke
Niu, Ling-zhi
Wang, Yuan-ping
Zheng, Ya-juan
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-23
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Abstract EN
Nuclear factor- (erythroid-derived 2-) like 2 (Nrf2) is a regulator of many processes of life, and it plays an important role in antioxidant, anti-inflammatory, and antifibrotic responses and in cancer.
This review is focused on the potential mechanism of Nrf2 in the occurrence and development of ocular diseases.
Also, several Nrf2 inducers, including noncoding RNAs and exogenous compounds, which control the expression of Nrf2 through different pathways, are discussed in ocular disease models and ocular cells, protecting them from dysfunctional changes.
Therefore, Nrf2 might be a potential target of protecting ocular cells from various stresses and preventing ocular diseases.
American Psychological Association (APA)
Wang, Ming-xuan& Zhao, Jing& Zhang, Hong& Li, Ke& Niu, Ling-zhi& Wang, Yuan-ping…[et al.]. 2020. Potential Protective and Therapeutic Roles of the Nrf2 Pathway in Ocular Diseases: An Update. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-22.
https://search.emarefa.net/detail/BIM-1206046
Modern Language Association (MLA)
Wang, Ming-xuan…[et al.]. Potential Protective and Therapeutic Roles of the Nrf2 Pathway in Ocular Diseases: An Update. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-22.
https://search.emarefa.net/detail/BIM-1206046
American Medical Association (AMA)
Wang, Ming-xuan& Zhao, Jing& Zhang, Hong& Li, Ke& Niu, Ling-zhi& Wang, Yuan-ping…[et al.]. Potential Protective and Therapeutic Roles of the Nrf2 Pathway in Ocular Diseases: An Update. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-22.
https://search.emarefa.net/detail/BIM-1206046
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1206046