Oxidative Stress in Cell Death and Cardiovascular Diseases
Joint Authors
Xu, Tao
Ding, Wei
Ji, Xiaoyu
Ao, Xiang
Liu, Ying
Yu, Wanpeng
Wang, Jianxun
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-11-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
ROS functions as a second messenger and modulates multiple signaling pathways under the physiological conditions.
However, excessive intracellular ROS causes damage to the molecular components of the cell, which promotes the pathogenesis of various human diseases.
Cardiovascular diseases are serious threats to human health with extremely high rates of morbidity and mortality.
Dysregulation of cell death promotes the pathogenesis of cardiovascular diseases and is the clinical target during the disease treatment.
Numerous studies show that ROS production is closely linked to the cell death process and promotes the occurrence and development of the cardiovascular diseases.
In this review, we summarize the regulation of intracellular ROS, the roles of ROS played in the development of cardiovascular diseases, and the programmed cell death induced by intracellular ROS.
We also focus on anti-ROS system and the potential application of anti-ROS strategy in the treatment of cardiovascular diseases.
American Psychological Association (APA)
Xu, Tao& Ding, Wei& Ji, Xiaoyu& Ao, Xiang& Liu, Ying& Yu, Wanpeng…[et al.]. 2019. Oxidative Stress in Cell Death and Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1206050
Modern Language Association (MLA)
Xu, Tao…[et al.]. Oxidative Stress in Cell Death and Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1206050
American Medical Association (AMA)
Xu, Tao& Ding, Wei& Ji, Xiaoyu& Ao, Xiang& Liu, Ying& Yu, Wanpeng…[et al.]. Oxidative Stress in Cell Death and Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1206050
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1206050