Application of Acupuncture to Attenuate Immune Responses and Oxidative Stress in Postoperative Cognitive Dysfunction: What Do We Know So Far?
Joint Authors
Chang, Raymond Chuen-Chung
Ho, Yuen-Shan
Zhao, Fei-Yi
Yeung, Wing-Fai
Wong, Gordon Tin-Chun
Zhang, Hong-Qi
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-15
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Abstract EN
Postoperative cognitive dysfunction (POCD) is a common sequela following surgery and hospitalization.
The prevention and management of POCD are important during clinical practice.
POCD more commonly affects elderly patients who have undergone major surgery and can result in major decline in quality of life for both patients and their families.
Acupuncture has been suggested as an effective intervention for many neurological disorders.
In recent years, there are increasing interest in the use of acupuncture to prevent and treat POCD.
In this review, we summarized the clinical and preclinical evidence of acupuncture on POCD using a narrative approach and discussed the potential mechanisms involved.
The experimental details and findings of studies were summarized in tables and analyzed.
Most of the clinical studies suggested that acupuncture before surgery could reduce the incidence of POCD and reduce the levels of systematic inflammatory markers.
However, their reliability is limited by methodological flaws.
Animal studies showed that acupuncture reduced cognitive impairment and the associated pathology after various types of surgery.
It is possible that acupuncture modulates inflammation, oxidative stress, synaptic changes, and other cellular events to mitigate POCD.
In conclusion, acupuncture is a potential intervention for POCD.
More clinical studies with good research design are required to confirm its effectiveness.
At the same time, findings from animal studies will help reveal the protective mechanisms, in which systematic inflammation is likely to play a major role.
American Psychological Association (APA)
Ho, Yuen-Shan& Zhao, Fei-Yi& Yeung, Wing-Fai& Wong, Gordon Tin-Chun& Zhang, Hong-Qi& Chang, Raymond Chuen-Chung. 2020. Application of Acupuncture to Attenuate Immune Responses and Oxidative Stress in Postoperative Cognitive Dysfunction: What Do We Know So Far?. Oxidative Medicine and Cellular Longevity،Vol. 2020, no. 2020, pp.1-21.
https://search.emarefa.net/detail/BIM-1206105
Modern Language Association (MLA)
Ho, Yuen-Shan…[et al.]. Application of Acupuncture to Attenuate Immune Responses and Oxidative Stress in Postoperative Cognitive Dysfunction: What Do We Know So Far?. Oxidative Medicine and Cellular Longevity No. 2020 (2020), pp.1-21.
https://search.emarefa.net/detail/BIM-1206105
American Medical Association (AMA)
Ho, Yuen-Shan& Zhao, Fei-Yi& Yeung, Wing-Fai& Wong, Gordon Tin-Chun& Zhang, Hong-Qi& Chang, Raymond Chuen-Chung. Application of Acupuncture to Attenuate Immune Responses and Oxidative Stress in Postoperative Cognitive Dysfunction: What Do We Know So Far?. Oxidative Medicine and Cellular Longevity. 2020. Vol. 2020, no. 2020, pp.1-21.
https://search.emarefa.net/detail/BIM-1206105
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1206105