The Biopsychosocial Burden of Prostate Biopsy at the Time of Its Indication, Procedure, and Pathological Report
Joint Authors
Rejowski, Ronald F.
Simões, Fabiano A.
Sanches, Brunno C. F.
Voris, Brunno R. I.
Reis, Leonardo Oliveira
Laranja, Walker Wendell
Alonso, João Carlos Cardoso
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Purpose.
To explore the burden of prostate biopsy at the time of its indication, procedure, and pathological report in the prostate cancer-screening scenario that is neglected and underestimated in the literature.
Methods.
Prostate biopsy was offered to 47 consecutive patients with prostate-specific antigen (PSA) over 4 ng/dl or suspicious digital rectal examination (DRE) of whom 16 had undergone a biopsy.
Comprehensive validated questionnaires at Time 0 (prebiopsy), Time 1 (before diagnosis, 20 days after biopsy), and Time 2 (after diagnosis, 40 days after biopsy) accessed patients' erectile (IIEF-5) and voiding (IPSS) functions, Beck scales measured anxiety (BAI), hopelessness (BHS), and depression (BDI), added to the emotional thermometers including five visual analog scales for distress, anxiety, depression, anger, and need for help.
The Mann-Whitney or Friedman tests were obtained among times and studied variables.
Results.
Prostate biopsy did not significantly impact patients' erectile and voiding functions while a higher Beck anxiety index (BAI) was observed at Time 0 (6.89 ± 6.33) compared to Time 1 (4.83 ± 2.87), p=0.0214, and to Time 2 (4.22 ± 4.98), p=0.0178.
At Time 0, patients that experienced a previous biopsy presented higher distress (3.1 ± 3.0 vs.
1.6 ± 2.3), p=0.043, and emotional suffering thermometer scores (2.3 ± 3.3 vs.
0.9 ± 2.4) compared to those undergoing the first biopsy, p=0.036.
At Time 2, patients with positive biopsies compared with those with negative ones showed no significant difference in outcome scores.
The sample power was >90%.
Conclusions.
To be considered in patients' counseling and care, the current study supports the hypothesis that the peak burden of prostate biopsy occurs at the time of its indication and might be higher for those experiencing rebiopsy, significantly impacting patients' psychosocial domains.
Trial Approval. This trial is registered under number NCT03783741.
American Psychological Association (APA)
Laranja, Walker Wendell& Sanches, Brunno C. F.& Voris, Brunno R. I.& Alonso, João Carlos Cardoso& Simões, Fabiano A.& Rejowski, Ronald F.…[et al.]. 2019. The Biopsychosocial Burden of Prostate Biopsy at the Time of Its Indication, Procedure, and Pathological Report. Prostate Cancer،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1206786
Modern Language Association (MLA)
Laranja, Walker Wendell…[et al.]. The Biopsychosocial Burden of Prostate Biopsy at the Time of Its Indication, Procedure, and Pathological Report. Prostate Cancer No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1206786
American Medical Association (AMA)
Laranja, Walker Wendell& Sanches, Brunno C. F.& Voris, Brunno R. I.& Alonso, João Carlos Cardoso& Simões, Fabiano A.& Rejowski, Ronald F.…[et al.]. The Biopsychosocial Burden of Prostate Biopsy at the Time of Its Indication, Procedure, and Pathological Report. Prostate Cancer. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1206786
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1206786