![](/images/graphics-bg.png)
Angiosarcoma of the Scalp and Face: A Dosimetric Comparison of HDR Surface Applicator Brachytherapy and VMAT
Joint Authors
Mitra, Devarati
Pei, Yaguang
Buzurovic, Ivan
Devlin, Phillip M.
Thornton, Katherine
Raut, Chandrajit P.
Baldini, Elizabeth H.
Lam, Miranda B.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
Angiosarcoma of the face and scalp is a rare disease with high rates of recurrence.
The optimal treatment approach is not well defined.
This study presents a dosimetric comparison of high-dose-rate surface applicator (HDR-SA) brachytherapy to volumetric-modulated arc therapy (VMAT).
Methods.
Between 2011 and 2018, 12 patients with primary or recurrent angiosarcoma of the face or scalp were treated with HDR-SA brachytherapy using CT-based planning at our institution.
For comparison, deliverable VMAT plans for each patient were generated, and dose distribution was compared to the delivered HDR-SA brachytherapy plans.
Results.
Both VMAT and HDR-SA brachytherapy plans delivered good coverage of the clinical target.
However, the dose distribution of VMAT was significantly different from HDR-SA brachytherapy across a variety of parameters.
Mean doses to the lacrimal gland, orbit, lens, and cochlea were significantly higher with HDR-SA brachytherapy vs.
VMAT.
Brain Dmax, V80%, and V50% were also significantly higher with HDR-SA brachytherapy.
Conclusions.
There may be dosimetric advantages to VMAT over HDR-SA brachytherapy for many patients.
However, individual tumor location, patient anatomy, and treatment reproducibility may result in HDR-SA brachytherapy being the preferred technique in a subset of patients.
Ultimately, a personalized approach is likely to be the optimal treatment plan.
American Psychological Association (APA)
Mitra, Devarati& Pei, Yaguang& Buzurovic, Ivan& Devlin, Phillip M.& Thornton, Katherine& Raut, Chandrajit P.…[et al.]. 2020. Angiosarcoma of the Scalp and Face: A Dosimetric Comparison of HDR Surface Applicator Brachytherapy and VMAT. Complexity،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1207353
Modern Language Association (MLA)
Mitra, Devarati…[et al.]. Angiosarcoma of the Scalp and Face: A Dosimetric Comparison of HDR Surface Applicator Brachytherapy and VMAT. Complexity No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1207353
American Medical Association (AMA)
Mitra, Devarati& Pei, Yaguang& Buzurovic, Ivan& Devlin, Phillip M.& Thornton, Katherine& Raut, Chandrajit P.…[et al.]. Angiosarcoma of the Scalp and Face: A Dosimetric Comparison of HDR Surface Applicator Brachytherapy and VMAT. Complexity. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1207353
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207353