Prevalence of Cognitive Impairment and Its Predictors among HIVAIDS Patients on Antiretroviral Therapy in Jimma University Medical Center, Southwest Ethiopia
Joint Authors
Yitbarek, Getachew Yideg
Mossie Ayana, Andualem
Bariso Gare, Moyeta
Garedew Woldeamanuel, Gashaw
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Cognitive impairment among human immunodeficiency virus (HIV) infected patients can lead to treatment nonadherence, faster progression of the illness, disability, and bed ridden state if we fail to detect it early.
However, there is scarcity of previous published studies in Ethiopia on the assessment of cognitive impairment among HIV-positive patients.
Hence, this study aimed to determine the prevalence and associated factors of cognitive impairment among HIV-positive patients receiving antiretroviral therapy (ART) at Jimma University Medical Center, Ethiopia.
Methods.
Hospital-based cross-sectional study was conducted among 328 HIV-positive patients attending Jimma University Medical Center, Ethiopia.
Data were collected from a face-to-face interview and review of medical records using semistructured questionnaire.
Validated International HIV Dementia Scale (IHDS) was used to screen for cognitive impairment.
Data was analyzed using SPSS version 20.
Results.
A total of 328 (191 females and 137 males) HIV-positive patients were included in the study with a response rate of 97.04%.
The prevalence of cognitive impairment among HIV-positive patients was 35.7%.
Factors significantly associated with cognitive impairment were age group of 41−64 years (adjusted odds ratio [AOR] = 3.1, 95% confidence interval [CI] (1.3, 7.4)], plasma HIV-1 RNA load between 1.7log10 and 3log10 copies/ml [AOR = 2.2, 95% CI (1.1,4.3)] and ≥ 3log10 copies/ml [AOR = 7.5, 95% CI (2.6, 21.5)], khat chewing [AOR = 4.4, 95% CI (2.3, 8.3)], and clinical stage III of the disease [AOR = 5.6, 95% CI (1.7, 19.2)].
Conclusion.
Despite the use of ART, the burden of cognitive impairment among HIV patients was high.
Older age, khat chewing, advanced stage of the disease, and higher viral load were the independent factors associated with cognitive impairment.
Thus, continuous screening of cognitive impairment, identification of the possible risk factors, and proper management strategy should be designed.
American Psychological Association (APA)
Yitbarek, Getachew Yideg& Mossie Ayana, Andualem& Bariso Gare, Moyeta& Garedew Woldeamanuel, Gashaw. 2019. Prevalence of Cognitive Impairment and Its Predictors among HIVAIDS Patients on Antiretroviral Therapy in Jimma University Medical Center, Southwest Ethiopia. Psychiatry Journal،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1207514
Modern Language Association (MLA)
Yitbarek, Getachew Yideg…[et al.]. Prevalence of Cognitive Impairment and Its Predictors among HIVAIDS Patients on Antiretroviral Therapy in Jimma University Medical Center, Southwest Ethiopia. Psychiatry Journal No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1207514
American Medical Association (AMA)
Yitbarek, Getachew Yideg& Mossie Ayana, Andualem& Bariso Gare, Moyeta& Garedew Woldeamanuel, Gashaw. Prevalence of Cognitive Impairment and Its Predictors among HIVAIDS Patients on Antiretroviral Therapy in Jimma University Medical Center, Southwest Ethiopia. Psychiatry Journal. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1207514
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207514