Epigenetic Clock: DNA Methylation in Aging
Joint Authors
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-08
Country of Publication
Egypt
No. of Pages
9
Abstract EN
Aging, which is accompanied by decreased organ function and increased disease incidence, limits human lifespan and has attracted investigators for thousands of years.
In recent decades, with the rapid development of biology, scientists have shown that epigenetic modifications, especially DNA methylation, are key regulators involved in this process.
Regular fluctuations in global DNA methylation levels have been shown to accurately estimate biological age and disease prognosis.
In this review, we discuss recent findings regarding the relationship between variations in DNA methylation level patterns and aging.
In addition, we introduce the known mechanisms by which DNA methylation regulators affect aging and related diseases.
As more studies uncover the mechanisms by which DNA methylation regulates aging, antiaging interventions and treatments for related diseases may be developed that enable human life extension.
American Psychological Association (APA)
Jiang, Shuang& Guo, Yuchen. 2020. Epigenetic Clock: DNA Methylation in Aging. Stem Cells International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1207585
Modern Language Association (MLA)
Jiang, Shuang& Guo, Yuchen. Epigenetic Clock: DNA Methylation in Aging. Stem Cells International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1207585
American Medical Association (AMA)
Jiang, Shuang& Guo, Yuchen. Epigenetic Clock: DNA Methylation in Aging. Stem Cells International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1207585
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207585