Oral Mesenchymal StemProgenitor Cells: The Immunomodulatory Masters
Joint Authors
Fawzy El-Sayed, Karim M.
Dörfer, Christof E.
Zhou, Li-li
Liu, Wei
Wu, Yan-min
Sun, Wei-lian
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-25
Country of Publication
Egypt
No. of Pages
16
Abstract EN
Oral mesenchymal stem/progenitor cells (MSCs) are renowned in the field of tissue engineering/regeneration for their multilineage differentiation potential and easy acquisition.
These cells encompass the periodontal ligament stem/progenitor cells (PDLSCs), the dental pulp stem/progenitor cells (DPSCs), the stem/progenitor cells from human exfoliated deciduous teeth (SHED), the gingival mesenchymal stem/progenitor cells (GMSCs), the stem/progenitor cells from the apical papilla (SCAP), the dental follicle stem/progenitor cells (DFSCs), the bone marrow mesenchymal stem/progenitor cells (BM-MSCs) from the alveolar bone proper, and the human periapical cyst-mesenchymal stem cells (hPCy-MSCs).
Apart from their remarkable regenerative potential, oral MSCs possess the capacity to interact with an inflammatory microenvironment.
Although inflammation might affect the properties of oral MSCs, they could inversely exert a multitude of immunological actions to the local inflammatory microenvironment.
The present review discusses the current understanding about the immunomodulatory role of oral MSCs both in periodontitis and systemic diseases, their “double-edged sword” uniqueness in inflammatory regulation, their affection of the immune system, and the underlying mechanisms, involving oral MSC-derived extracellular vesicles.
American Psychological Association (APA)
Zhou, Li-li& Liu, Wei& Wu, Yan-min& Sun, Wei-lian& Dörfer, Christof E.& Fawzy El-Sayed, Karim M.. 2020. Oral Mesenchymal StemProgenitor Cells: The Immunomodulatory Masters. Stem Cells International،Vol. 2020, no. 2020, pp.1-16.
https://search.emarefa.net/detail/BIM-1207600
Modern Language Association (MLA)
Zhou, Li-li…[et al.]. Oral Mesenchymal StemProgenitor Cells: The Immunomodulatory Masters. Stem Cells International No. 2020 (2020), pp.1-16.
https://search.emarefa.net/detail/BIM-1207600
American Medical Association (AMA)
Zhou, Li-li& Liu, Wei& Wu, Yan-min& Sun, Wei-lian& Dörfer, Christof E.& Fawzy El-Sayed, Karim M.. Oral Mesenchymal StemProgenitor Cells: The Immunomodulatory Masters. Stem Cells International. 2020. Vol. 2020, no. 2020, pp.1-16.
https://search.emarefa.net/detail/BIM-1207600
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207600