Induced Pluripotent Stem Cells in Dental and Nondental Tissue Regeneration: A Review of an Unexploited Potential
Joint Authors
Fawzy El-Sayed, Karim M.
Radwan, Israa Ahmed
Rady, Dina
Abbass, Marwa M. S.
El Moshy, Sara
AbuBakr, Nermeen
Dörfer, Christof E.
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-24, 24 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-29
Country of Publication
Egypt
No. of Pages
24
Abstract EN
Cell-based therapies currently represent the state of art for tissue regenerative treatment approaches for various diseases and disorders.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, using vectors carrying definite transcription factors, have manifested a breakthrough in regenerative medicine, relying on their pluripotent nature and ease of generation in large amounts from various dental and nondental tissues.
In addition to their potential applications in regenerative medicine and dentistry, iPSCs can also be used in disease modeling and drug testing for personalized medicine.
The current review discusses various techniques for the production of iPSC-derived osteogenic and odontogenic progenitors, the therapeutic applications of iPSCs, and their regenerative potential in vivo and in vitro.
Through the present review, we aim to explore the potential applications of iPSCs in dental and nondental tissue regeneration and to highlight different protocols used for the generation of different tissues and cell lines from iPSCs.
American Psychological Association (APA)
Radwan, Israa Ahmed& Rady, Dina& Abbass, Marwa M. S.& El Moshy, Sara& AbuBakr, Nermeen& Dörfer, Christof E.…[et al.]. 2020. Induced Pluripotent Stem Cells in Dental and Nondental Tissue Regeneration: A Review of an Unexploited Potential. Stem Cells International،Vol. 2020, no. 2020, pp.1-24.
https://search.emarefa.net/detail/BIM-1207632
Modern Language Association (MLA)
Radwan, Israa Ahmed…[et al.]. Induced Pluripotent Stem Cells in Dental and Nondental Tissue Regeneration: A Review of an Unexploited Potential. Stem Cells International No. 2020 (2020), pp.1-24.
https://search.emarefa.net/detail/BIM-1207632
American Medical Association (AMA)
Radwan, Israa Ahmed& Rady, Dina& Abbass, Marwa M. S.& El Moshy, Sara& AbuBakr, Nermeen& Dörfer, Christof E.…[et al.]. Induced Pluripotent Stem Cells in Dental and Nondental Tissue Regeneration: A Review of an Unexploited Potential. Stem Cells International. 2020. Vol. 2020, no. 2020, pp.1-24.
https://search.emarefa.net/detail/BIM-1207632
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207632