Mesenchymal Stem Cell-Based Therapy for Allergic Rhinitis
Joint Authors
Sha, Jichao
Sun, Liwei
Meng, Cuida
Zhu, Dongdong
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-10
Country of Publication
Egypt
No. of Pages
6
Abstract EN
Allergic rhinitis (AR) is a prevalent disorder that causes a significant and often underestimated health burden for individuals and society.
The current drug treatment cannot essentially deal with the regulation of the allergic reaction, while the allergic symptoms could be alleviated.
Mesenchymal stem cells (MSCs) bear a variety of properties, such as the ability to differentiate into various cell lineages, to secrete soluble factors crucial for cell survival and proliferation, to migrate to the exact site of injury, and to modulate the immune response.
Clinical studies have been extensively conducted in MSCs as the models for varieties of diseases such as neurological diseases.
Due to their immunomodulatory properties, the MSCs have gradually been believed to become one of the promising strategies for AR treatments although so far the MSCs-mediated treatment for AR is still at animal experiments stage.
Fully understanding the roles and mechanisms of MSCs immunomodulatory effects serves as the prerequisite that will be beneficial to the application of MSCs-based AR clinical treatment methods.
In this review article, we highlighted the recent research advances and give a brief perspective in the future study of the MSCs-mediated therapeutic application in AR treatments.
American Psychological Association (APA)
Sun, Liwei& Sha, Jichao& Meng, Cuida& Zhu, Dongdong. 2020. Mesenchymal Stem Cell-Based Therapy for Allergic Rhinitis. Stem Cells International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1207668
Modern Language Association (MLA)
Sun, Liwei…[et al.]. Mesenchymal Stem Cell-Based Therapy for Allergic Rhinitis. Stem Cells International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1207668
American Medical Association (AMA)
Sun, Liwei& Sha, Jichao& Meng, Cuida& Zhu, Dongdong. Mesenchymal Stem Cell-Based Therapy for Allergic Rhinitis. Stem Cells International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1207668
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207668