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Functions of Circular RNAs in Regulating Adipogenesis of Mesenchymal Stem Cells
Joint Authors
Wang, Fanglin
Wang, Shoushuai
Fan, Jun
Li, Zhiyuan
Li, Xiang
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-01
Country of Publication
Egypt
No. of Pages
12
Abstract EN
The mesenchymal stem cells (MSCs) are known as highly plastic stem cells and can differentiate into specialized tissues such as adipose tissue, osseous tissue, muscle tissue, and nervous tissue.
The differentiation of mesenchymal stem cells is very important in regenerative medicine.
Their differentiation process is regulated by signaling pathways of epigenetic, transcriptional, and posttranscriptional levels.
Circular RNA (circRNA), a class of noncoding RNAs generated from protein-coding genes, plays a pivotal regulatory role in many biological processes.
Accumulated studies have demonstrated that several circRNAs participate in the cell differentiation process of mesenchymal stem cells in vitro and in vivo.
In the current review, characteristics and functions of circRNAs in stem cell differentiation will be discussed.
The mechanism and key role of circRNAs in regulating mesenchymal stem cell differentiation, especially adipogenesis, will be reviewed and discussed.
Understanding the roles of these circRNAs will present us with a more comprehensive signal path network of modulating stem cell differentiation and help us discover potential biomarkers and therapeutic targets in clinic.
American Psychological Association (APA)
Wang, Fanglin& Li, Xiang& Li, Zhiyuan& Wang, Shoushuai& Fan, Jun. 2020. Functions of Circular RNAs in Regulating Adipogenesis of Mesenchymal Stem Cells. Stem Cells International،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1207708
Modern Language Association (MLA)
Wang, Fanglin…[et al.]. Functions of Circular RNAs in Regulating Adipogenesis of Mesenchymal Stem Cells. Stem Cells International No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1207708
American Medical Association (AMA)
Wang, Fanglin& Li, Xiang& Li, Zhiyuan& Wang, Shoushuai& Fan, Jun. Functions of Circular RNAs in Regulating Adipogenesis of Mesenchymal Stem Cells. Stem Cells International. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1207708
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207708