Estimating the Relative Stiffness between a Hepatic Lesion and the Liver Parenchyma through Biomechanical Simulations of the Breathing Process
Joint Authors
Martínez-Sanchis, S.
Rupérez, M. J.
Pareja, E.
Brugger, S.
Borzacchiello, D.
López-Andújar, R.
Monserrat, C.
Nadal, E.
Source
Mathematical Problems in Engineering
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-25
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
In this paper, a method to in vivo estimate the relative stiffness between a hepatic lesion and the liver parenchyma is presented.
This method is based on the finite element simulation of the deformation that the liver undergoes during the breathing process.
Boundary conditions are obtained through a registration algorithm known as Coherent Point Drift (CPD), which compares the liver form in two phases of the breathing process.
Finally, the relative stiffness of the tumour with respect to the liver parenchyma is calculated by means of a Genetic Algorithm, which does a blind search of this parameter.
The relative stiffness together with the clinical information of the patient can be used to establish the type of hepatic lesion.
The developed methodology was first applied to a test case, i.e., to a control case where the parameters were known, in order to verify its validity.
After that, the method was applied to two real cases and low errors were obtained.
American Psychological Association (APA)
Martínez-Sanchis, S.& Rupérez, M. J.& Nadal, E.& Pareja, E.& Brugger, S.& Borzacchiello, D.…[et al.]. 2018. Estimating the Relative Stiffness between a Hepatic Lesion and the Liver Parenchyma through Biomechanical Simulations of the Breathing Process. Mathematical Problems in Engineering،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1207908
Modern Language Association (MLA)
Martínez-Sanchis, S.…[et al.]. Estimating the Relative Stiffness between a Hepatic Lesion and the Liver Parenchyma through Biomechanical Simulations of the Breathing Process. Mathematical Problems in Engineering No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1207908
American Medical Association (AMA)
Martínez-Sanchis, S.& Rupérez, M. J.& Nadal, E.& Pareja, E.& Brugger, S.& Borzacchiello, D.…[et al.]. Estimating the Relative Stiffness between a Hepatic Lesion and the Liver Parenchyma through Biomechanical Simulations of the Breathing Process. Mathematical Problems in Engineering. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1207908
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207908