Herb-Derived Products: Natural Tools to Delay and Counteract Stem Cell Senescence
Joint Authors
Abruzzo, Provvidenza M.
Canaider, Silvia
Pizzuti, Valeria
Pampanella, Luca
Casadei, Raffaella
Facchin, Federica
Ventura, Carlo
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-28, 28 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-08
Country of Publication
Egypt
No. of Pages
28
Abstract EN
Cellular senescence plays a very important role in organismal aging increasing with age and in age-related diseases (ARDs).
This process involves physiological, structural, biochemical, and molecular changes of cells, leading to a characteristic trait referred to “senescence-associated secretory phenotype (SASP).” In particular, with aging, stem cells (SCs) in situ exhibit a diminished capacity of self-renewal and show a decline in their functionality.
The identification of interventions able to prevent the accumulation of senescent SCs in the organism or to pretreat cultured multipotent mesenchymal stromal cells (MSCs) prior to employing them for cell therapy is a main purpose of medical research.
Many approaches have been investigated and resulted effective to prevent or counteract SC senescence in humans, as well as other animal models.
In this work, we have reviewed the chance of using a number of herb-derived products as novel tools in the treatment of cell senescence, highlighting the efficacy of these agents, often still far from being clearly understood.
American Psychological Association (APA)
Abruzzo, Provvidenza M.& Canaider, Silvia& Pizzuti, Valeria& Pampanella, Luca& Casadei, Raffaella& Facchin, Federica…[et al.]. 2020. Herb-Derived Products: Natural Tools to Delay and Counteract Stem Cell Senescence. Stem Cells International،Vol. 2020, no. 2020, pp.1-28.
https://search.emarefa.net/detail/BIM-1207918
Modern Language Association (MLA)
Abruzzo, Provvidenza M.…[et al.]. Herb-Derived Products: Natural Tools to Delay and Counteract Stem Cell Senescence. Stem Cells International No. 2020 (2020), pp.1-28.
https://search.emarefa.net/detail/BIM-1207918
American Medical Association (AMA)
Abruzzo, Provvidenza M.& Canaider, Silvia& Pizzuti, Valeria& Pampanella, Luca& Casadei, Raffaella& Facchin, Federica…[et al.]. Herb-Derived Products: Natural Tools to Delay and Counteract Stem Cell Senescence. Stem Cells International. 2020. Vol. 2020, no. 2020, pp.1-28.
https://search.emarefa.net/detail/BIM-1207918
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207918