Dual Role of MSC-Derived Exosomes in Tumor Development
Joint Authors
Song, Hui
Bie, Qingli
Zhao, Rou
Chen, Xinke
Zhang, Bin
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-09
Country of Publication
Egypt
No. of Pages
11
Abstract EN
Mesenchymal stem cells (MSCs) are a class of adult stem cells derived from the mesoderm.
They can self-renew, have multidirectional differentiation potential, and can differentiate into a variety of mesenchymal tissues.
MSCs can produce a large number of exosomes, which can mediate information exchange and transmission between cells in the tumor microenvironment under conditions of rest or stress.
Recent studies have reported conflicting findings regarding the effect of MSC-derived exosomes on tumors.
Some studies have suggested that MSC-derived exosomes can promote tumor growth and metastasis, but others have reported that they can inhibit tumor cell growth.
Here, we investigate the two sides of the debate regarding the effect of MSC-derived exosomes on tumors and analyze the reasons for the divergent findings.
American Psychological Association (APA)
Zhao, Rou& Chen, Xinke& Song, Hui& Bie, Qingli& Zhang, Bin. 2020. Dual Role of MSC-Derived Exosomes in Tumor Development. Stem Cells International،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1207965
Modern Language Association (MLA)
Zhao, Rou…[et al.]. Dual Role of MSC-Derived Exosomes in Tumor Development. Stem Cells International No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1207965
American Medical Association (AMA)
Zhao, Rou& Chen, Xinke& Song, Hui& Bie, Qingli& Zhang, Bin. Dual Role of MSC-Derived Exosomes in Tumor Development. Stem Cells International. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1207965
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1207965