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Macroalgae Sargassum cristaefolium Extract Inhibits Proinflammatory Cytokine Expression in BALBC Mice
Joint Authors
Prasedya, Eka Sunarwidhi
Martyasari, Ni Wayan Riyani
Abidin, Angga Susmana
Pebriani, Sonia Ardilla
Ilhami, Bq Tri Khairina
Frediansyah, Andri
Sunarwidhi, Anggit Listyacahyani
Widyastuti, Sri
Sunarpi, Haji
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-10
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Ultraviolet radiation (UVR) which could induce skin damage and skin disease is a growing concern due to the increase in global warming.
Brown macroalgae Sargassum cristaefolium has been recognized to exhibit UV protective activities.
However, the mechanism of its photoprotective activity remains unclear.
The purpose of this study is to investigate the potential mechanism of S.
cristaefolium’s photoprotective activity against UV radiation.
Phytochemical analyses revealed valuable bioactive compounds in SCE, such as fucoxanthin which is widely known as an anti-inflammatory carotenoid.
Treatment with SCE before UV-A radiation show reduced levels of wrinkles and desquamation.
Interestingly, SCE treatment induces the skin healing process after UV radiation.
SCE effectively inhibited proinflammatory TNF-α and IL-6 expression while increasing IL-10 production in the BALB/c mice skin.
Current results suggest that SCE potentially protects the skin by attenuation of inflammatory cytokines.
In addition, SCE demonstrates promising antibacterial activity (MIC = 1.302 µg/mL) against Staphylococcus aureus.
Overall, SCE could be a source of an effective anti-inflammatory agent protecting against UV irradiation-induced skin damages.
American Psychological Association (APA)
Prasedya, Eka Sunarwidhi& Martyasari, Ni Wayan Riyani& Abidin, Angga Susmana& Pebriani, Sonia Ardilla& Ilhami, Bq Tri Khairina& Frediansyah, Andri…[et al.]. 2020. Macroalgae Sargassum cristaefolium Extract Inhibits Proinflammatory Cytokine Expression in BALBC Mice. Scientifica،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1208286
Modern Language Association (MLA)
Prasedya, Eka Sunarwidhi…[et al.]. Macroalgae Sargassum cristaefolium Extract Inhibits Proinflammatory Cytokine Expression in BALBC Mice. Scientifica No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1208286
American Medical Association (AMA)
Prasedya, Eka Sunarwidhi& Martyasari, Ni Wayan Riyani& Abidin, Angga Susmana& Pebriani, Sonia Ardilla& Ilhami, Bq Tri Khairina& Frediansyah, Andri…[et al.]. Macroalgae Sargassum cristaefolium Extract Inhibits Proinflammatory Cytokine Expression in BALBC Mice. Scientifica. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1208286
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1208286