The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal StemStromal Cells
Joint Authors
Goldberg, Anna Carla
Paladino, Fernanda Vieira
de Moraes Rodrigues, Juliana
da Silva, Aline
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-11
Country of Publication
Egypt
No. of Pages
7
Abstract EN
The benefits attributed to mesenchymal stem/stromal cells (MSC) in cell therapy applications are mainly attributed to the secretion of factors, which exhibit immunomodulatory and anti-inflammatory effects and stimulate angiogenesis.
Despite the desirable features such as high proliferation levels, multipotency, and immune response regulation, there are important variables that must be considered.
Although presenting similar morphological aspects, MSC collected from different tissues can form heterogeneous cellular populations and, therefore, manifest functional differences.
Thus, the source of MSC should be a factor to be considered in the development of novel therapies.
The following text presents an updated review of recent research outcomes related to Wharton’s jelly mesenchymal stem/stromal cells (WJ-MSC), harvested from umbilical cords and considered novel and potential candidates for the development of cell-based approaches.
This text highlights information on how WJ-MSC affect immune responses in comparison with other sources of MSC.
American Psychological Association (APA)
Paladino, Fernanda Vieira& de Moraes Rodrigues, Juliana& da Silva, Aline& Goldberg, Anna Carla. 2019. The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal StemStromal Cells. Stem Cells International،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1208700
Modern Language Association (MLA)
Paladino, Fernanda Vieira…[et al.]. The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal StemStromal Cells. Stem Cells International No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1208700
American Medical Association (AMA)
Paladino, Fernanda Vieira& de Moraes Rodrigues, Juliana& da Silva, Aline& Goldberg, Anna Carla. The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal StemStromal Cells. Stem Cells International. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1208700
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1208700