Mechanism of Action of Icariin in Bone Marrow Mesenchymal Stem Cells
Joint Authors
Yu, Chao-Chao
Yang, Aofei
He, Chengjian
Li, Zhanghua
Lu, Qilin
Li, Hao
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-04
Country of Publication
Egypt
No. of Pages
12
Abstract EN
Osteoporosis, femoral head necrosis, and congenital bone defects are orthopedic disorders characterized by reduced bone generation and insufficient bone mass.
Bone regenerative therapy primarily relies on the bone marrow mesenchymal stem cells (BMSCs) and their ability to differentiate osteogenically.
Icariin (ICA) is the active ingredient of Herba epimedii, a common herb used in traditional Chinese medicine (TCM) formulations, and can effectively enhance BMSC proliferation and osteogenesis.
However, the underlying mechanism of ICA action in BMSCs is not completely clear.
In this review, we provide an overview of the studies on the role and mechanism of action of ICA in BMSCs, to provide greater insights into its potential clinical use in bone regeneration.
American Psychological Association (APA)
Yang, Aofei& Yu, Chao-Chao& Lu, Qilin& Li, Hao& Li, Zhanghua& He, Chengjian. 2019. Mechanism of Action of Icariin in Bone Marrow Mesenchymal Stem Cells. Stem Cells International،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1209156
Modern Language Association (MLA)
Yang, Aofei…[et al.]. Mechanism of Action of Icariin in Bone Marrow Mesenchymal Stem Cells. Stem Cells International No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1209156
American Medical Association (AMA)
Yang, Aofei& Yu, Chao-Chao& Lu, Qilin& Li, Hao& Li, Zhanghua& He, Chengjian. Mechanism of Action of Icariin in Bone Marrow Mesenchymal Stem Cells. Stem Cells International. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1209156
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1209156