Multiscale Stem Cell Technologies for Osteonecrosis of the Femoral Head
Joint Authors
Chai, Wei
Ma, Xibo
Wang, Yi
Tian, Jie
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-08
Country of Publication
Egypt
No. of Pages
13
Abstract EN
The last couple of decades have seen brilliant progress in stem cell therapies, including native, genetically modified, and engineered stem cells, for osteonecrosis of the femoral head (ONFH).
In vitro studies evaluate the effect of endogenous or exogenous factor or gene regulation on osteogenic phenotype maintenance and/or differentiation towards osteogenic lineage.
The preclinical and clinical outcomes accelerate the clinical translation.
Bone marrow mesenchymal stem cells and adipose-derived stem cells have demonstrated better effects in the treatment of femoral head necrosis.
Various materials have been used widely in the ONFH treatment in both preclinical and clinical trials.
In a word, in vivo and multiscale efforts are expected to overcome obstacles in the approaches for treating ONFH and provide clinical relevance and commercial strategies in the future.
Therefore, we will discuss the above aspects in this paper and present our opinions.
American Psychological Association (APA)
Wang, Yi& Ma, Xibo& Chai, Wei& Tian, Jie. 2019. Multiscale Stem Cell Technologies for Osteonecrosis of the Femoral Head. Stem Cells International،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1209860
Modern Language Association (MLA)
Wang, Yi…[et al.]. Multiscale Stem Cell Technologies for Osteonecrosis of the Femoral Head. Stem Cells International No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1209860
American Medical Association (AMA)
Wang, Yi& Ma, Xibo& Chai, Wei& Tian, Jie. Multiscale Stem Cell Technologies for Osteonecrosis of the Femoral Head. Stem Cells International. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1209860
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1209860