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Exploring Postoperative Cognitive Dysfunction and Delirium in Noncardiac Surgery Using MRI: A Systematic Review
Joint Authors
Huang, Chenxi
Mårtensson, Johan
Gögenur, Ismail
Asghar, Mohammad Sohail
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-18
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Surgical patients are at high risk of developing postoperative cognitive dysfunction (POCD) and postoperative delirium (POD).
POCD and POD are associated with increased morbidity and mortality and worsening functional outcomes leading to severe socioeconomic consequences for the patient and the society in general.
Magnetic resonance imaging (MRI) offers a unique opportunity to study the anatomy and function of the brain.
MRI thus plays an important role in elucidating the neuronal component of POCD and POD.
Our aim has been to systematically gather MRI findings that are related to POCD and POD.
Systematic searches were conducted in PubMed, EMBASE, and PsycINFO: MRI studies investigating patients with POCD as identified by perioperative cognitive testing or patients with delirium identified postoperatively by the Confusion Assessment Method.
A total of ten eligible papers were included with a total of 269 surgical patients, 36 patient controls, and 55 healthy controls who all underwent MRI examination.
These studies suggested that reduction of thalamic and hippocampal volumes and reduction of cerebral blood flow may be associated with POCD, while presurgery/preexisting and postoperative white matter pathology may be associated with POD.
However, the evidence from these studies is rather weak.
Future MRI studies are warranted to verify the current findings.
American Psychological Association (APA)
Huang, Chenxi& Mårtensson, Johan& Gögenur, Ismail& Asghar, Mohammad Sohail. 2018. Exploring Postoperative Cognitive Dysfunction and Delirium in Noncardiac Surgery Using MRI: A Systematic Review. Neural Plasticity،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1209950
Modern Language Association (MLA)
Huang, Chenxi…[et al.]. Exploring Postoperative Cognitive Dysfunction and Delirium in Noncardiac Surgery Using MRI: A Systematic Review. Neural Plasticity No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1209950
American Medical Association (AMA)
Huang, Chenxi& Mårtensson, Johan& Gögenur, Ismail& Asghar, Mohammad Sohail. Exploring Postoperative Cognitive Dysfunction and Delirium in Noncardiac Surgery Using MRI: A Systematic Review. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1209950
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1209950