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Noninvasive Brain Stimulations for Unilateral Spatial Neglect after Stroke: A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Controlled Trials
Joint Authors
Conforto, Adriana Bastos
Luvizutto, Gustavo José
de Souza, Juli Thomaz
da Silva, Taís Regina
Kashiwagi, Flávio Taira
El Dib, Regina
Gomaa, Huda
Gawish, Nermeen
Suzumura, Erica Aranha
Winckler, Fernanda Cristina
Bazan, Rodrigo
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-25, 25 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-28
Country of Publication
Egypt
No. of Pages
25
Main Subjects
Abstract EN
Background.
Unilateral spatial neglect (USN) is the most frequent perceptual disorder after stroke.
Noninvasive brain stimulation (NIBS) is a tool that has been used in the rehabilitation process to modify cortical excitability and improve perception and functional capacity.
Objective.
To assess the impact of NIBS on USN after stroke.
Methods.
An extensive search was conducted up to July 2016.
Studies were selected if they were controlled and noncontrolled trials examining transcranial direct current stimulation (tDCS), repetitive transcranial magnetic stimulation (rTMS), and theta burst stimulation (TBS) in USN after stroke, with outcomes measured by standardized USN and functional tests.
Results.
Twelve RCTs (273 participants) and 4 non-RCTs (94 participants) proved eligible.
We observed a benefit in overall USN measured by the line bisection test with NIBS in comparison to sham (SMD −2.35, 95% CI −3.72, −0.98; p=0.0001); the rTMS yielded results that were consistent with the overall meta-analysis (SMD −2.82, 95% CI −3.66, −1.98; p=0.09).
The rTMS compared with sham also suggested a benefit in overall USN measured by Motor-Free Visual Perception Test at both 1 Hz (SMD 1.46, 95% CI 0.73, 2.20; p<0.0001) and 10 Hz (SMD 1.19, 95% CI 0.48, 1.89; p=0.54).
There was also a benefit in overall USN measured by Albert’s test and the line crossing test with 1 Hz rTMS compared to sham (SMD 2.04, 95% CI 1.14, 2.95; p<0.0001).
Conclusions.
The results suggest a benefit of NIBS on overall USN, and we conclude that rTMS is more efficacious compared to sham for USN after stroke.
American Psychological Association (APA)
Kashiwagi, Flávio Taira& El Dib, Regina& Gomaa, Huda& Gawish, Nermeen& Suzumura, Erica Aranha& da Silva, Taís Regina…[et al.]. 2018. Noninvasive Brain Stimulations for Unilateral Spatial Neglect after Stroke: A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Controlled Trials. Neural Plasticity،Vol. 2018, no. 2018, pp.1-25.
https://search.emarefa.net/detail/BIM-1209965
Modern Language Association (MLA)
Kashiwagi, Flávio Taira…[et al.]. Noninvasive Brain Stimulations for Unilateral Spatial Neglect after Stroke: A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Controlled Trials. Neural Plasticity No. 2018 (2018), pp.1-25.
https://search.emarefa.net/detail/BIM-1209965
American Medical Association (AMA)
Kashiwagi, Flávio Taira& El Dib, Regina& Gomaa, Huda& Gawish, Nermeen& Suzumura, Erica Aranha& da Silva, Taís Regina…[et al.]. Noninvasive Brain Stimulations for Unilateral Spatial Neglect after Stroke: A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Controlled Trials. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-25.
https://search.emarefa.net/detail/BIM-1209965
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1209965