Stem Cell-Derived Hepatocyte-Like Cells as Model for Viral Hepatitis Research
Joint Authors
Xia, Yuchen
Deng, Wanyan
Qu, Bingqian
Wang, Jingjing
Zhang, Fang
Zhang, Cindy
Dao Thi, Viet Loan
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-12
Country of Publication
Egypt
No. of Pages
11
Abstract EN
Viral hepatitis, the leading cause of liver diseases worldwide, is induced upon infection with hepatotropic viruses, including hepatitis A, B, C, D, and E virus.
Due to their obligate intracellular lifestyles, culture systems for efficient viral replication are vital.
Although basic and translational research on viral hepatitis has been performed for many years, conventional hepatocellular culture systems are not optimal.
These studies have greatly benefited from recent efforts on improving cell culture models for virus replication and infection studies.
Here we summarize the use of human stem cell-derived hepatocyte-like cells for hepatotropic virus infection studies, including the dissection of virus-host interactions and virus-induced pathogenesis as well as the identification and validation of novel antiviral agents.
American Psychological Association (APA)
Wang, Jingjing& Qu, Bingqian& Zhang, Fang& Zhang, Cindy& Deng, Wanyan& Dao Thi, Viet Loan…[et al.]. 2019. Stem Cell-Derived Hepatocyte-Like Cells as Model for Viral Hepatitis Research. Stem Cells International،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1210028
Modern Language Association (MLA)
Wang, Jingjing…[et al.]. Stem Cell-Derived Hepatocyte-Like Cells as Model for Viral Hepatitis Research. Stem Cells International No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1210028
American Medical Association (AMA)
Wang, Jingjing& Qu, Bingqian& Zhang, Fang& Zhang, Cindy& Deng, Wanyan& Dao Thi, Viet Loan…[et al.]. Stem Cell-Derived Hepatocyte-Like Cells as Model for Viral Hepatitis Research. Stem Cells International. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1210028
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210028