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Challenges and Controversies in Human Mesenchymal Stem Cell Therapy
Joint Authors
Łęgosz, Paweł
Drela, Katarzyna
Lukomska, Barbara
Zuba-Surma, Ewa K.
Stanaszek, Luiza
Sarzynska, Sylwia
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-09
Country of Publication
Egypt
No. of Pages
10
Abstract EN
Stem cell therapy is being intensely investigated within the last years.
Expectations are high regarding mesenchymal stem cell (MSC) treatment in translational medicine.
However, many aspects concerning MSC therapy should be profoundly defined.
Due to a variety of approaches that are investigated, potential effects of stem cell therapy are not transparent.
On the other hand, most results of MSC administration in vivo have confirmed their safety and showed promising beneficial outcomes.
However, the therapeutic effects of MSC-based treatment are still not spectacular and there is a potential risk related to MSC applications into specific cell niche that should be considered in long-term observations and follow-up outcomes.
In this review, we intend to address some problems and critically discuss the complex nature of MSCs in the context of their effective and safe applications in regenerative medicine in different diseases including graft versus host disease (GvHD) and cardiac, neurological, and orthopedic disorders.
American Psychological Association (APA)
Lukomska, Barbara& Stanaszek, Luiza& Zuba-Surma, Ewa K.& Łęgosz, Paweł & Sarzynska, Sylwia& Drela, Katarzyna. 2019. Challenges and Controversies in Human Mesenchymal Stem Cell Therapy. Stem Cells International،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1210043
Modern Language Association (MLA)
Lukomska, Barbara…[et al.]. Challenges and Controversies in Human Mesenchymal Stem Cell Therapy. Stem Cells International No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1210043
American Medical Association (AMA)
Lukomska, Barbara& Stanaszek, Luiza& Zuba-Surma, Ewa K.& Łęgosz, Paweł & Sarzynska, Sylwia& Drela, Katarzyna. Challenges and Controversies in Human Mesenchymal Stem Cell Therapy. Stem Cells International. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1210043
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210043