Diffusion Tensor Imaging Evaluation of Neural Network Development in Patients Undergoing Therapeutic Repetitive Transcranial Magnetic Stimulation following Stroke
Joint Authors
Abo, Masahiro
Kondo, Takahiro
Yamada, Naoki
Momosaki, Ryo
Ueda, Ryo
Kakuda, Wataru
Hada, Takuya
Sasaki, Nobuyuki
Hara, Takatoshi
Senoo, Atsushi
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
We aimed to investigate plastic changes in cerebral white matter structures using diffusion tensor imaging following a 15-day stroke rehabilitation program.
We compared the detection of cerebral plasticity between generalized fractional anisotropy (GFA), a novel tool for investigating white matter structures, and fractional anisotropy (FA).
Low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) of 2400 pulses applied to the nonlesional hemisphere and 240 min intensive occupation therapy (OT) daily over 15 days.
Motor function was evaluated using the Fugl-Meyer assessment (FMA) and Wolf Motor Function Test (WMFT).
Patients underwent diffusion tensor magnetic resonance imaging (MRI) on admission and discharge, from which bilateral FA and GFA values in Brodmann area (BA) 4 and BA6 were calculated.
Motor function improved following treatment (p<0.001).
Treatment increased GFA values for both the lesioned and nonlesioned BA4 (p<0.05, p<0.001, resp.).
Changes in GFA value for BA4 of the lesioned hemisphere were significantly inversely correlated with changes in WMFT scores (R2=0.363, p<0.05).
Our findings indicate that the GFA may have a potentially more useful ability than FA to detect changes in white matter structures in areas of fiber intersection for any such future investigations.
American Psychological Association (APA)
Yamada, Naoki& Ueda, Ryo& Kakuda, Wataru& Momosaki, Ryo& Kondo, Takahiro& Hada, Takuya…[et al.]. 2018. Diffusion Tensor Imaging Evaluation of Neural Network Development in Patients Undergoing Therapeutic Repetitive Transcranial Magnetic Stimulation following Stroke. Neural Plasticity،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1210055
Modern Language Association (MLA)
Yamada, Naoki…[et al.]. Diffusion Tensor Imaging Evaluation of Neural Network Development in Patients Undergoing Therapeutic Repetitive Transcranial Magnetic Stimulation following Stroke. Neural Plasticity No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1210055
American Medical Association (AMA)
Yamada, Naoki& Ueda, Ryo& Kakuda, Wataru& Momosaki, Ryo& Kondo, Takahiro& Hada, Takuya…[et al.]. Diffusion Tensor Imaging Evaluation of Neural Network Development in Patients Undergoing Therapeutic Repetitive Transcranial Magnetic Stimulation following Stroke. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1210055
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210055