Xenointoxication of a Rabbit for the Control of the Common Bed Bug Cimex lectularius L. Using Ivermectin
Joint Authors
Sheele, Johnathan
Ridge, Gale E.
Elmer, Wade
Gaines, Stephanie
Li, Xiaolin
Schlatzer, Danie
McClure-Brinton, Kim
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Human bed bug infestations have undergone a recent global resurgence.
The human antiparasitic drug ivermectin has been proposed as a strategy to help control bed bug infestations, but in vivo data are lacking.
We allowed separate populations of the common bed bug, Cimex lectularius L., to feed once on a rabbit before and after it was injected subcutaneously with 0.3 mg/kg of ivermectin, and bed bug morbidity and mortality were recorded.
Ivermectin levels in the rabbit were measured using high-performance liquid chromatography and mass spectroscopy.
Ivermectin blood levels of ∼2 ng/mL caused reductions in bed bug fecundity, and levels of >8 ng/mL caused bed bug death and long-term morbidity including reductions in refeeding, mobility, reproduction, and molting.
Gut bacterial cultures from the fed bed bugs showed that ivermectin altered the bed bug gut microbiome.
American Psychological Association (APA)
Ridge, Gale E.& Elmer, Wade& Gaines, Stephanie& Li, Xiaolin& Schlatzer, Danie& McClure-Brinton, Kim…[et al.]. 2019. Xenointoxication of a Rabbit for the Control of the Common Bed Bug Cimex lectularius L. Using Ivermectin. Scientifica،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1210174
Modern Language Association (MLA)
Ridge, Gale E.…[et al.]. Xenointoxication of a Rabbit for the Control of the Common Bed Bug Cimex lectularius L. Using Ivermectin. Scientifica No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1210174
American Medical Association (AMA)
Ridge, Gale E.& Elmer, Wade& Gaines, Stephanie& Li, Xiaolin& Schlatzer, Danie& McClure-Brinton, Kim…[et al.]. Xenointoxication of a Rabbit for the Control of the Common Bed Bug Cimex lectularius L. Using Ivermectin. Scientifica. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1210174
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210174