Proteolytic Remodeling of Perineuronal Nets: Effects on Synaptic Plasticity and Neuronal Population Dynamics
Joint Authors
Conant, Katherine
Villapol, Sonia
Lorenzo Bozzelli, P.
Alaiyed, Seham
Kim, Eunyoung
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-04
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The perineuronal net (PNN) represents a lattice-like structure that is prominently expressed along the soma and proximal dendrites of parvalbumin- (PV-) positive interneurons in varied brain regions including the cortex and hippocampus.
It is thus apposed to sites at which PV neurons receive synaptic input.
Emerging evidence suggests that changes in PNN integrity may affect glutamatergic input to PV interneurons, a population that is critical for the expression of synchronous neuronal population discharges that occur with gamma oscillations and sharp-wave ripples.
The present review is focused on the composition of PNNs, posttranslation modulation of PNN components by sulfation and proteolysis, PNN alterations in disease, and potential effects of PNN remodeling on neuronal plasticity at the single-cell and population level.
American Psychological Association (APA)
Lorenzo Bozzelli, P.& Alaiyed, Seham& Kim, Eunyoung& Villapol, Sonia& Conant, Katherine. 2018. Proteolytic Remodeling of Perineuronal Nets: Effects on Synaptic Plasticity and Neuronal Population Dynamics. Neural Plasticity،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1210178
Modern Language Association (MLA)
Lorenzo Bozzelli, P.…[et al.]. Proteolytic Remodeling of Perineuronal Nets: Effects on Synaptic Plasticity and Neuronal Population Dynamics. Neural Plasticity No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1210178
American Medical Association (AMA)
Lorenzo Bozzelli, P.& Alaiyed, Seham& Kim, Eunyoung& Villapol, Sonia& Conant, Katherine. Proteolytic Remodeling of Perineuronal Nets: Effects on Synaptic Plasticity and Neuronal Population Dynamics. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1210178
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210178