Changes in Resting-State Connectivity following Melody-Based Therapy in a Patient with Aphasia
Joint Authors
Bitan, Tali
Simic, Tijana
Saverino, Cristina
Jones, Cheryl
Glazer, Joanna
Collela, Brenda
Wiseman-Hakes, Catherine
Green, Robin
Rochon, Elizabeth
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-29
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Melody-based treatments for patients with aphasia rely on the notion of preserved musical abilities in the RH, following left hemisphere damage.
However, despite evidence for their effectiveness, the role of the RH is still an open question.
We measured changes in resting-state functional connectivity following melody-based intervention, to identify lateralization of treatment-related changes.
A patient with aphasia due to left frontal and temporal hemorrhages following traumatic brain injuries (TBI) more than three years earlier received 48 sessions of melody-based intervention.
Behavioral measures improved and were maintained at the 8-week posttreatment follow-up.
Resting-state fMRI data collected before and after treatment showed an increase in connectivity between motor speech control areas (bilateral supplementary motor areas and insulae) and RH language areas (inferior frontal gyrus pars triangularis and pars opercularis).
This change, which was specific for the RH, was greater than changes in a baseline interval measured before treatment.
No changes in RH connectivity were found in a matched control TBI patient scanned at the same intervals.
These results are compatible with a compensatory role for RH language areas following melody-based intervention.
They further suggest that this therapy intervenes at the level of the interface between language areas and speech motor control areas necessary for language production.
American Psychological Association (APA)
Bitan, Tali& Simic, Tijana& Saverino, Cristina& Jones, Cheryl& Glazer, Joanna& Collela, Brenda…[et al.]. 2018. Changes in Resting-State Connectivity following Melody-Based Therapy in a Patient with Aphasia. Neural Plasticity،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1210256
Modern Language Association (MLA)
Bitan, Tali…[et al.]. Changes in Resting-State Connectivity following Melody-Based Therapy in a Patient with Aphasia. Neural Plasticity No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1210256
American Medical Association (AMA)
Bitan, Tali& Simic, Tijana& Saverino, Cristina& Jones, Cheryl& Glazer, Joanna& Collela, Brenda…[et al.]. Changes in Resting-State Connectivity following Melody-Based Therapy in a Patient with Aphasia. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1210256
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210256