Reorganization of the Action Observation Network and Sensory-Motor System in Children with Unilateral Cerebral Palsy: An fMRI Study
Joint Authors
Guzzetta, Andrea
Ferrari, Adriano
Cioni, Giovanni
Sgandurra, Giuseppina
Biagi, Laura
Fogassi, Leonardo
Sicola, Elisa
Tosetti, Michela
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-25
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Little is known about the action observation network (AON) in children with unilateral cerebral palsy (UCP).
Using fMRI, we aimed to explore AON and sensory-motor network (SMN) in UCP children and compare them to typically developed (TD) children and analyse the relationship between AON (re-)organization and several neurophysiological and clinical measures.
Twelve UCP children were assessed with clinical scales and transcranial magnetic stimulation (TMS).
For the fMRI study, they underwent a paradigm based on observation of complex and simple object-manipulation tasks executed by dominant and nondominant hand.
Moreover, UCP and TD children carried out a further fMRI session to explore SMN in both an active motor and passive sensory task.
AON in the UCP group showed higher lateralization, negatively related to performances on clinical scales, and had greater activation of unaffected hemisphere as compared to the bilateral representation in the TD group.
In addition, a good congruence was found between bilateral or contralateral activation of AON and activation of SMN and TMS data.
These findings indicate that our paradigm might be useful in exploring AON and the response to therapy in UCP subjects.
American Psychological Association (APA)
Sgandurra, Giuseppina& Biagi, Laura& Fogassi, Leonardo& Sicola, Elisa& Ferrari, Adriano& Guzzetta, Andrea…[et al.]. 2018. Reorganization of the Action Observation Network and Sensory-Motor System in Children with Unilateral Cerebral Palsy: An fMRI Study. Neural Plasticity،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1210300
Modern Language Association (MLA)
Sgandurra, Giuseppina…[et al.]. Reorganization of the Action Observation Network and Sensory-Motor System in Children with Unilateral Cerebral Palsy: An fMRI Study. Neural Plasticity No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1210300
American Medical Association (AMA)
Sgandurra, Giuseppina& Biagi, Laura& Fogassi, Leonardo& Sicola, Elisa& Ferrari, Adriano& Guzzetta, Andrea…[et al.]. Reorganization of the Action Observation Network and Sensory-Motor System in Children with Unilateral Cerebral Palsy: An fMRI Study. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1210300
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210300