Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury
Joint Authors
Liu, Xuehong
Zhou, Jingying
Huo, Xue
Botchway, Benson O. A.
Xu, Luyao
Meng, Xiaofang
Zhang, Songou
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Spinal cord injury (SCI) causes a high rate of morbidity and disability.
The clinical features of SCI are divided into acute, subacute, and chronic phases according to its pathophysiological events.
The mammalian target of rapamycin (mTOR) signaling pathway plays an important role in cell death and inflammation in the acute phase and neuroregeneration in the subacute/chronic phases at different times.
Resveratrol has the potential of regulating cell growth, proliferation, metabolism, and angiogenesis through the mTOR signaling pathway.
Herein, we explicate the role of resveratrol in the repair of SCI through the inhibition of the mTOR signaling pathway.
The inhibition of the mTOR pathway by resveratrol has the potential of serving as a neuronal restorative mechanism following SCI.
American Psychological Association (APA)
Zhou, Jingying& Huo, Xue& Botchway, Benson O. A.& Xu, Luyao& Meng, Xiaofang& Zhang, Songou…[et al.]. 2018. Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury. Neural Plasticity،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1210363
Modern Language Association (MLA)
Zhou, Jingying…[et al.]. Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury. Neural Plasticity No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1210363
American Medical Association (AMA)
Zhou, Jingying& Huo, Xue& Botchway, Benson O. A.& Xu, Luyao& Meng, Xiaofang& Zhang, Songou…[et al.]. Beneficial Effects of Resveratrol-Mediated Inhibition of the mTOR Pathway in Spinal Cord Injury. Neural Plasticity. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1210363
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1210363